STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q5K6Z6_CRYNJUncharacterized protein; Belongs to the heat shock protein 70 family. (733 aa)    
Predicted Functional Partners:
Q5KPD7_CRYNJ
Heat shock protein sks2 (Heat shock cognate protein hsc1), putative; Belongs to the heat shock protein 70 family.
  
0.999
Q5KLW0_CRYNJ
Uncharacterized protein.
  
0.995
Q5K7H6_CRYNJ
Protein disulfide-isomerase.
  
 0.992
FES1
Hsp70 nucleotide exchange factor FES1; Functions as a nucleotide exchange factor (NEF) for Hsp70 chaperones which accelerates the release of ADP. Required for fully efficient Hsp70-mediated folding of proteins (By similarity). Belongs to the FES1 family.
   
 
 0.981
Q5KH58_CRYNJ
Cation-transporting ATPase, putative.
   
 0.979
Q5KMH4_CRYNJ
Protein kinase/endoribonuclease, putative.
   
 0.977
A0A0S2LIV9
Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.
   
 0.972
Q5KHB5_CRYNJ
ER-associated protein catabolism-related protein, putative.
   
 0.955
Q5KPQ5_CRYNJ
RanBD1 domain-containing protein.
   
 0.951
Q5KIE7_CRYNJ
Nsp1_C domain-containing protein.
    
  0.945
Your Current Organism:
Cryptococcus neoformans
NCBI taxonomy Id: 214684
Other names: C. neoformans var. neoformans JEC21, Cryptococcus neoformans JEC21, Cryptococcus neoformans var. neoformans JEC21, Cryptococcus neoformans var. neoformans serotype D JEC21, Cryptococcus neoformans var. neoformans strain JEC21, Filobasidiella neoformans var. neoformans strain JEC21
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