STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q5K8I5_CRYNJMAP kinase kinase kinase. (1486 aa)    
Predicted Functional Partners:
Q5KM40_CRYNJ
Two-component response regulator, putative.
   
 0.996
Q5KN75_CRYNJ
MAP kinase kinase, putative.
  
0.993
Q5KE91_CRYNJ
RWD domain-containing protein.
    
   0.704
Q5KQ00_CRYNJ
Two-component sensor molecule, putative.
    
 
 0.700
Q5KGY3_CRYNJ
Mitogen-activated protein kinase kinase, putative.
  
 
0.649
Q5KKP1_CRYNJ
MAP kinase kinase, putative.
  
 
0.640
Q5KE48_CRYNJ
Transcription factor, putative.
   
 
 0.619
Q5K7R5_CRYNJ
Transferase, putative.
    
 
 0.613
A0A0S2M685
SH3 domain-containing protein; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.
    
 
 0.583
Q5KKD9_CRYNJ
Protein-histidine kinase, putative.
   
 
 0.554
Your Current Organism:
Cryptococcus neoformans
NCBI taxonomy Id: 214684
Other names: C. neoformans var. neoformans JEC21, Cryptococcus neoformans JEC21, Cryptococcus neoformans var. neoformans JEC21, Cryptococcus neoformans var. neoformans serotype D JEC21, Cryptococcus neoformans var. neoformans strain JEC21, Filobasidiella neoformans var. neoformans strain JEC21
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.