STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NTE1Lysophospholipase NTE1; Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis. Responsible for the rapid PC turnover in response to inositol, elevated temperatures, or when choline is present in the growth medium (By similarity); Belongs to the NTE family. (1621 aa)    
Predicted Functional Partners:
Q5KBN1_CRYNJ
Glycerophosphodiester phosphodiesterase, putative.
  
 
 0.926
PLB1
Phospholipase B; Exhibits phospholipase B (PLB), lysophospholipase (LPL) and lysophospholipase/transacylase (LPTA) activities; Belongs to the lysophospholipase family.
   
 
 0.923
Q5KPB8_CRYNJ
Endoplasmic reticulum protein, putative; Belongs to the membrane-bound acyltransferase family.
   
 
 0.910
APTH1_CRYNJ
Acyl-protein thioesterase 1; Hydrolyzes fatty acids from S-acylated cysteine residues in proteins with a strong preference for palmitoylated G-alpha proteins over other acyl substrates.
  
 
  0.901
Q5KGZ9_CRYNJ
ATP binding protein, putative; Belongs to the STXBP/unc-18/SEC1 family.
 
 
    0.767
Q5KA63_CRYNJ
Glutamate synthase (NADH), putative.
  
 
 0.743
Q5K8G1_CRYNJ
NADPH:adrenodoxin oxidoreductase, mitochondrial.
  
 
 0.720
Q5KCJ3_CRYNJ
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
   
 0.708
Q5KKB2_CRYNJ
Uncharacterized protein.
   
 0.708
Q5KP84_CRYNJ
Protein serine/threonine kinase, putative.
   
 0.708
Your Current Organism:
Cryptococcus neoformans
NCBI taxonomy Id: 214684
Other names: C. neoformans var. neoformans JEC21, Cryptococcus neoformans JEC21, Cryptococcus neoformans var. neoformans JEC21, Cryptococcus neoformans var. neoformans serotype D JEC21, Cryptococcus neoformans var. neoformans strain JEC21, Filobasidiella neoformans var. neoformans strain JEC21
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