STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TSC103-ketodihydrosphingosine reductase TSC10; Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS); Belongs to the short-chain dehydrogenases/reductases (SDR) family. (335 aa)    
Predicted Functional Partners:
Q5KJC6_CRYNJ
Uncharacterized protein.
     
 0.991
Q5KNA1_CRYNJ
Serine C-palmitoyltransferase, putative.
     
 0.991
Q5KIH9_CRYNJ
D-erythro-sphingosine kinase, putative.
     
 0.957
Q5KNJ8_CRYNJ
Fatty acid desaturase, putative.
   
 
 0.951
Q5KM26_CRYNJ
Sphingosine hydroxylase, putative; Belongs to the sterol desaturase family.
    
 0.949
Q5KG85_CRYNJ
TLC domain-containing protein.
     
 0.946
Q5KG86_CRYNJ
Sphingosine N-acyltransferase, putative.
   
 
 0.946
Q5KMQ6_CRYNJ
Longevity-assurance protein, putative.
     
 0.946
Q5KIU3_CRYNJ
Ceramidase, putative.
     
 0.934
Q5KF67_CRYNJ
acidPPc domain-containing protein.
    
 0.927
Your Current Organism:
Cryptococcus neoformans
NCBI taxonomy Id: 214684
Other names: C. neoformans var. neoformans JEC21, Cryptococcus neoformans JEC21, Cryptococcus neoformans var. neoformans JEC21, Cryptococcus neoformans var. neoformans serotype D JEC21, Cryptococcus neoformans var. neoformans strain JEC21, Filobasidiella neoformans var. neoformans strain JEC21
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.