STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A4P9ZRX4Thiamine diphosphate-binding protein. (384 aa)    
Predicted Functional Partners:
A0A4V1J4L5
Dihydrolipoyllysine-residue succinyltransferase E2 component.
 0.977
A0A4P9ZZW9
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.949
A0A4P9ZVN5
Single hybrid motif-containing protein.
  
 0.932
A0A4Q0A3T5
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.932
A0A4Q0A308
Dihydrolipoyl dehydrogenase.
  
 0.926
A0A4P9ZMH1
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
  
 0.924
A0A4P9ZUM6
Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 0.905
A0A4P9ZKG2
Uncharacterized protein.
  
 0.889
A0A4P9ZKW6
Succinate-CoA ligase subunit beta.
  
 0.889
A0A4P9ZK68
Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 0.885
Your Current Organism:
Dimargaris cristalligena
NCBI taxonomy Id: 215637
Other names: D. cristalligena
Server load: low (24%) [HD]