STRINGSTRING
def protein (Burkholderia cenocepacia) - STRING interaction network
"def" - Peptide deformylase in Burkholderia cenocepacia
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second shell of interactors
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Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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defPeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (167 aa)    
Predicted Functional Partners:
fmt
Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus (330 aa)
 
  0.977
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20 (103 aa)
 
 
  0.956
rplT
50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (119 aa)
 
 
  0.956
rplQ
annotation not available (131 aa)
   
      0.933
rplV
50S ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) (109 aa)
   
      0.933
rpsE
30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family (172 aa)
   
 
  0.930
rpsC
30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (266 aa)
   
 
 
  0.930
rplX
50S ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5’-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (102 aa)
   
      0.929
rpsI
annotation not available (130 aa)
   
 
  0.926
rplR
50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (121 aa)
   
 
      0.925
Your Current Organism:
Burkholderia cenocepacia
NCBI taxonomy Id: 216591
Other names: B. cenocepacia J2315, Burkholderia cenocepacia, Burkholderia cenocepacia J2315, Burkholderia cenocepacia str. J2315, Burkholderia cepacia J2315, Burkholderia cepacia str. J2315
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