STRINGSTRING
metG protein (Burkholderia cenocepacia) - STRING interaction network
"metG" - Methionine--tRNA ligase in Burkholderia cenocepacia
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metGMethionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (718 aa)    
Predicted Functional Partners:
pheS
annotation not available (337 aa)
   
 
  0.968
BCAL1933
L-arabinose formyltransferase; Similar to the N-terminal region of Escherichia coli bifunctional polymyxin resistance arnA protein UniProt-P77398 (EMBL-AP009048 (660 aa) fasta scores- E()=1.3e-41, 42.173% id in 313 aa (315 aa)
   
 
  0.961
fmt
Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus (330 aa)
   
 
  0.961
metE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family (764 aa)
   
  0.943
metH2
annotation not available (355 aa)
     
 
  0.925
metH1
annotation not available (905 aa)
     
 
  0.925
ksgA
Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3’-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (275 aa)
 
   
  0.921
argS
annotation not available (593 aa)
   
 
  0.889
thrS
Threonine--tRNA ligase; Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction- L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr) (635 aa)
 
 
  0.887
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP (539 aa)
   
 
  0.886
Your Current Organism:
Burkholderia cenocepacia
NCBI taxonomy Id: 216591
Other names: B. cenocepacia J2315, Burkholderia cenocepacia, Burkholderia cenocepacia J2315, Burkholderia cenocepacia str. J2315, Burkholderia cepacia J2315, Burkholderia cepacia str. J2315
Server load: low (9%) [HD]