STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
makConserved protein; Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB (By similarity); Belongs to the aminoglycoside phosphotransferase family. (455 aa)    
Predicted Functional Partners:
treS
Trehalose synthase TreS; Involved in trehalose biosynthesis (protective effect). converts maltose to trehalose. mycobacteria can produce trehalose from glucose 6-phosphate and UDP-glucose (the OtsA-OtsB pathway) from glycogen-like alpha(1-->4)- linked glucose polymers (the TreY-TreZ pathway) and from maltose (the TreS pathway).
 0.999
glgE
Conserved glycosidase; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB; Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
 
 0.998
aglA
Alpha-glucosidase AglA; Involved in sugar metabolism (hydrolysis of terminal, non-reducing 1,4-linked d-glucose residues with release of d-glucose).
 0.995
glgB
1,4-alpha-glucan branching enzyme GlgB; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
  
 0.991
MMAR_4226
Glycosyl transferase; Function unknown; probably involved in cellular metabolism.
  
  
 0.986
malQ
4-alpha-glucanotransferase MalQ; Transfers a segment of a (1,4)-alpha-D-glucan to a new 4-position in an acceptor, which may be glucose or (1,4)-alpha-D-glucan.
 
 
 0.974
treS_1
Trehalose synthase TreS_1; Involved in trehalose biosynthesis (protective effect). converts maltose to trehalose. mycobacteria can produce trehalose from glucose 6-phosphate and UDP-glucose (the OtsA-OtsB pathway) from glycogen-like alpha(1-->4)- linked glucose polymers (the TreY-TreZ pathway) and from maltose (the TreS pathway).
 
 0.968
treZ
Maltooligosyltrehalose trehalohydrolase, TreZ; Involved in trehalose biosynthesis (protective effect). mycobacteria can produce trehalose from glucose 6- phosphate and UDP-glucose (the OtsA-OtsB pathway) from glycogen-like alpha(1-->4)-linked glucose polymers (the TreY-TreZ pathway) and from maltose (the TreS pathway).
 
  
 0.953
treY
Maltooligosyltrehalose synthase TreY; Involved in trehalose biosynthesis (protective effect). mycobacteria can produce trehalose from glucose 6- phosphate and UDP-glucose (the OtsA-OtsB pathway) from glycogen-like alpha(1-->4)-linked glucose polymers (the TreY-TreZ pathway).
 
  
 0.919
glgC
Glucose-1-phosphate adenylyltransferase GlgC; Involved in the biosynthesis of ADP-glucose, a building block, required in the biosynthesis of maltose-1-phosphate (M1P) and in the elongation reactions to produce linear alpha-1,4-glucans. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
     
 0.865
Your Current Organism:
Mycobacterium marinum
NCBI taxonomy Id: 216594
Other names: M. marinum M, Mycobacterium marinum M, Mycobacterium marinum str. M, Mycobacterium marinum strain M
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