node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cfp10A | moeB1 | MMAR_4063 | MMAR_1352 | 9.5 kDa culture filtrate antigen Cfp10A. | Molybdenum cofactor biosynthesis protein MoeB1; Possibly involved in molybdopterin metabolism (synthesis). | 0.995 |
cfp10A | thiG | MMAR_4063 | MMAR_0720 | 9.5 kDa culture filtrate antigen Cfp10A. | Thiamin biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.969 |
dxs1 | dxs2 | MMAR_2032 | MMAR_0276 | 1-deoxy-D-xylulose 5-phosphate synthase Dxs1; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 1-deoxy-D-xylulose 5-phosphate synthase Dxs2; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.905 |
dxs1 | thiG | MMAR_2032 | MMAR_0720 | 1-deoxy-D-xylulose 5-phosphate synthase Dxs1; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Thiamin biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.938 |
dxs1 | thiL | MMAR_2032 | MMAR_1735 | 1-deoxy-D-xylulose 5-phosphate synthase Dxs1; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Thiamine-monophosphate kinase ThiL; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. | 0.525 |
dxs2 | dxs1 | MMAR_0276 | MMAR_2032 | 1-deoxy-D-xylulose 5-phosphate synthase Dxs2; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 1-deoxy-D-xylulose 5-phosphate synthase Dxs1; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.905 |
dxs2 | thiD | MMAR_0276 | MMAR_0734 | 1-deoxy-D-xylulose 5-phosphate synthase Dxs2; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Phosphomethylpyrimidine kinase ThiD; Involved in thiamine biosynthesis. catalyzes the phosphorylation of HMP-P to HMP-PP [catalytic activity: ATP + 4-amino-2-methyl-5-phosphomethylpyrimidine = ADP + 4- amino-2-methyl-5-diphosphomethylpyrimidine]. | 0.545 |
dxs2 | thiG | MMAR_0276 | MMAR_0720 | 1-deoxy-D-xylulose 5-phosphate synthase Dxs2; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Thiamin biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.938 |
dxs2 | thiL | MMAR_0276 | MMAR_1735 | 1-deoxy-D-xylulose 5-phosphate synthase Dxs2; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Thiamine-monophosphate kinase ThiL; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. | 0.525 |
moeB1 | cfp10A | MMAR_1352 | MMAR_4063 | Molybdenum cofactor biosynthesis protein MoeB1; Possibly involved in molybdopterin metabolism (synthesis). | 9.5 kDa culture filtrate antigen Cfp10A. | 0.995 |
moeB1 | thiC | MMAR_1352 | MMAR_0735 | Molybdenum cofactor biosynthesis protein MoeB1; Possibly involved in molybdopterin metabolism (synthesis). | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.821 |
moeB1 | thiD | MMAR_1352 | MMAR_0734 | Molybdenum cofactor biosynthesis protein MoeB1; Possibly involved in molybdopterin metabolism (synthesis). | Phosphomethylpyrimidine kinase ThiD; Involved in thiamine biosynthesis. catalyzes the phosphorylation of HMP-P to HMP-PP [catalytic activity: ATP + 4-amino-2-methyl-5-phosphomethylpyrimidine = ADP + 4- amino-2-methyl-5-diphosphomethylpyrimidine]. | 0.820 |
moeB1 | thiE | MMAR_1352 | MMAR_0717 | Molybdenum cofactor biosynthesis protein MoeB1; Possibly involved in molybdopterin metabolism (synthesis). | Thiamine-phosphate pyrophosphorylase ThiE; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.846 |
moeB1 | thiG | MMAR_1352 | MMAR_0720 | Molybdenum cofactor biosynthesis protein MoeB1; Possibly involved in molybdopterin metabolism (synthesis). | Thiamin biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.974 |
moeB1 | thiL | MMAR_1352 | MMAR_1735 | Molybdenum cofactor biosynthesis protein MoeB1; Possibly involved in molybdopterin metabolism (synthesis). | Thiamine-monophosphate kinase ThiL; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. | 0.440 |
moeB1 | thiO | MMAR_1352 | MMAR_0718 | Molybdenum cofactor biosynthesis protein MoeB1; Possibly involved in molybdopterin metabolism (synthesis). | Involved in thiamine biosynthesis. | 0.402 |
moeB1 | thiS | MMAR_1352 | MMAR_0719 | Molybdenum cofactor biosynthesis protein MoeB1; Possibly involved in molybdopterin metabolism (synthesis). | Part of the thiamine biosynthesis operon. ThiS (thiaminS) is a 66 aa protein involved in sulphur transfer. It is coded in the THICEFSGH operon in E. coli. | 0.933 |
thiC | moeB1 | MMAR_0735 | MMAR_1352 | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | Molybdenum cofactor biosynthesis protein MoeB1; Possibly involved in molybdopterin metabolism (synthesis). | 0.821 |
thiC | thiD | MMAR_0735 | MMAR_0734 | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | Phosphomethylpyrimidine kinase ThiD; Involved in thiamine biosynthesis. catalyzes the phosphorylation of HMP-P to HMP-PP [catalytic activity: ATP + 4-amino-2-methyl-5-phosphomethylpyrimidine = ADP + 4- amino-2-methyl-5-diphosphomethylpyrimidine]. | 0.998 |
thiC | thiE | MMAR_0735 | MMAR_0717 | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | Thiamine-phosphate pyrophosphorylase ThiE; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.894 |