node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MMAR_0811 | MMAR_0813 | MMAR_0811 | MMAR_0813 | Transcriptional regulatory protein; Possibly involved in transcriptional mechanism. | Conserved hypothetical protein. | 0.797 |
MMAR_0811 | gpm1 | MMAR_0811 | MMAR_0814 | Transcriptional regulatory protein; Possibly involved in transcriptional mechanism. | Phosphoglycerate mutase 1 Gpm1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.865 |
MMAR_0811 | mshA | MMAR_0811 | MMAR_0812 | Transcriptional regulatory protein; Possibly involved in transcriptional mechanism. | Mannosyltransferase; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway. | 0.806 |
MMAR_0811 | regX3 | MMAR_0811 | MMAR_0816 | Transcriptional regulatory protein; Possibly involved in transcriptional mechanism. | Transcriptional regulatory protein part of the two-component regulatory system RegX3/SenX3. | 0.641 |
MMAR_0811 | senX3 | MMAR_0811 | MMAR_0815 | Transcriptional regulatory protein; Possibly involved in transcriptional mechanism. | Two-component sensor histidine kinase SenX3; Sensor part of a two-component regulatory system. probably forms part of a two-component regulatory system SenX3/RegX3; phosphorylates RegX3. | 0.746 |
MMAR_0813 | MMAR_0811 | MMAR_0813 | MMAR_0811 | Conserved hypothetical protein. | Transcriptional regulatory protein; Possibly involved in transcriptional mechanism. | 0.797 |
MMAR_0813 | gpm1 | MMAR_0813 | MMAR_0814 | Conserved hypothetical protein. | Phosphoglycerate mutase 1 Gpm1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.860 |
MMAR_0813 | mshA | MMAR_0813 | MMAR_0812 | Conserved hypothetical protein. | Mannosyltransferase; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway. | 0.901 |
MMAR_0813 | regX3 | MMAR_0813 | MMAR_0816 | Conserved hypothetical protein. | Transcriptional regulatory protein part of the two-component regulatory system RegX3/SenX3. | 0.662 |
MMAR_0813 | senX3 | MMAR_0813 | MMAR_0815 | Conserved hypothetical protein. | Two-component sensor histidine kinase SenX3; Sensor part of a two-component regulatory system. probably forms part of a two-component regulatory system SenX3/RegX3; phosphorylates RegX3. | 0.737 |
ethR | mshA | MMAR_5405 | MMAR_0812 | Transcriptional regulatory repressor protein (TetR-family) EthR; Regulates negatively the production of EthA. induced eth resistance when overexpressed in mycobacterium tuberculosis. | Mannosyltransferase; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway. | 0.786 |
gpm1 | MMAR_0811 | MMAR_0814 | MMAR_0811 | Phosphoglycerate mutase 1 Gpm1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | Transcriptional regulatory protein; Possibly involved in transcriptional mechanism. | 0.865 |
gpm1 | MMAR_0813 | MMAR_0814 | MMAR_0813 | Phosphoglycerate mutase 1 Gpm1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | Conserved hypothetical protein. | 0.860 |
gpm1 | mshA | MMAR_0814 | MMAR_0812 | Phosphoglycerate mutase 1 Gpm1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | Mannosyltransferase; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway. | 0.868 |
gpm1 | regX3 | MMAR_0814 | MMAR_0816 | Phosphoglycerate mutase 1 Gpm1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | Transcriptional regulatory protein part of the two-component regulatory system RegX3/SenX3. | 0.681 |
gpm1 | senX3 | MMAR_0814 | MMAR_0815 | Phosphoglycerate mutase 1 Gpm1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | Two-component sensor histidine kinase SenX3; Sensor part of a two-component regulatory system. probably forms part of a two-component regulatory system SenX3/RegX3; phosphorylates RegX3. | 0.745 |
mca | mshA | MMAR_4385 | MMAR_0812 | Mycothiol conjugate amidase Mca; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily. | Mannosyltransferase; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway. | 0.847 |
mca | mshB | MMAR_4385 | MMAR_4283 | Mycothiol conjugate amidase Mca; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily. | N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha- D-glucopyranoside deacetylase MshB; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway. | 0.477 |
mca | mshC | MMAR_4385 | MMAR_3110 | Mycothiol conjugate amidase Mca; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily. | cysteinyl-tRNA synthetase, MshC; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. | 0.829 |
mca | mshD | MMAR_4385 | MMAR_4864 | Mycothiol conjugate amidase Mca; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily. | Mycothiol acetyltransferase, MshD; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol. | 0.891 |