STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
echA5enoyl-CoA hydratase, EchA5; Oxidizes fatty acids using specific components [catalytic activity: (3S)-3-hydroxyacyl-CoA = TRANS-2(or 3)-enoyl-CoA + H(2)O]; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa)    
Predicted Functional Partners:
MMAR_1001
acyl-CoA dehydrogenase; May be involved in lipid degradation.
  
 0.926
echA4
enoyl-CoA hydratase, EchA4; [catalytic activity: (3S)-3-hydroxyacyl-CoA = TRANS- 2(or 3)-enoyl-CoA + H(2)O].
 
   
0.908
fadB2
3-hydroxybutyryl-CoA dehydrogenase FadB2; Butyrate/butanol-producing pathway [catalytic activity: (S)-3-hydroxybutanoyl-CoA + NADP+ = 3- acetoacetyl-CoA + NADPH].
 0.879
MMAR_1003
Conserved hypothetical regulatory protein; High domain identity with transcriptional repressors.
     
 0.879
fadE35
acyl-CoA dehydrogenase FadE35; Function unknown, but involved in lipid degradation.
  
 0.841
fadB3
3-hydroxybutyryl-CoA dehydrogenase FadB3; Thought to be involved in fatty acid degradation. FadB and FadA are the alpha and beta subunits of the multifunctional enzyme complex of the fatty acid degradation cycle [catalytic activity: (S)-3- hydroxybutanoyl-CoA + NADP+ = 3-acetoacetyl-CoA + NADPH].
 0.830
fadE25_2
acyl-CoA dehydrogenase FadE25_2; Function unknown, but involved in lipid degradation [catalytic activity: acyl-CoA + ETF = 2,3-dehydroacyl-CoA + reduced ETF].
  
 0.823
fadE2_1
acyl-CoA dehydrogenase FadE2_1; Function unknown, but involved in lipid degradation.
  
 0.823
fadE1
acyl-CoA dehydrogenase FadE1; Function unknown, but involved in lipid degradation.
  
 0.823
fadE2
acyl-CoA dehydrogenase FadE2; Function unknown, but involved in lipid degradation.
  
 0.823
Your Current Organism:
Mycobacterium marinum
NCBI taxonomy Id: 216594
Other names: M. marinum M, Mycobacterium marinum M, Mycobacterium marinum str. M, Mycobacterium marinum strain M
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.