STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMAR_1263Conserved hypothetical protein. (412 aa)    
Predicted Functional Partners:
MMAR_1264
Two-component system membrane associated sensor kinase.
  
 0.986
MMAR_1265
Sensor part of the two-component regulatory system.
 
  
 0.963
rsbU
Regulator of sigma subunit, anti-anti-sigma factor RsbU; May be involved in regulation of SigG.
 
 
0.887
MMAR_0738
Two-component sensor and regulator.
 
 
 0.781
MMAR_0214
Conserved hypothetical protein; Function unknown. domain identity suggests anti- anti-sigma regulatory factor; Belongs to the anti-sigma-factor antagonist family.
 
 
 0.704
MMAR_5186
Sensor-component of a two-component regulator.
 
 
0.698
MMAR_5181
Anti-anti-sigma regulatory factor; Function unknown; potential role in regulation of transcription; Belongs to the anti-sigma-factor antagonist family.
 
 
 0.687
MMAR_1227
Conserved hypothetical protein.
 
 
 0.676
MMAR_1631
Conserved hypothetical protein.
 
 
 0.674
rsbW
Anti-sigma factor RsbW; Binds to sigma and blocks its ability to form an RNA polymerase holoenzyme. regulates negatively SigF and negatively regulated by RsfA and RsfB.
  
 
 0.633
Your Current Organism:
Mycobacterium marinum
NCBI taxonomy Id: 216594
Other names: M. marinum M, Mycobacterium marinum M, Mycobacterium marinum str. M, Mycobacterium marinum strain M
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.