STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glsAGlutaminase GlsA; This family of enzymes deaminates glutamine to glutamate; Belongs to the glutaminase family. (320 aa)    
Predicted Functional Partners:
gltB
Ferredoxin-dependent glutamate synthase [NADPH] (large subunit) GltB; Probably involved in glutamate biosynthesis [catalytic activity: 2 L-glutamate + NADP(+) = L-glutamine + 2-oxoglutarate + NADPH].
    
 0.976
gadB
Glutamate decarboxylase, GadB; Catalyzes the production of GabA [catalytic activity: L-glutamate = 4-aminobutanoate + CO(2)]; Belongs to the group II decarboxylase family.
 
 
 0.953
murI
Glutamate racemase MurI; Provides the (R)-glutamate required for cell wall biosynthesis.
    
 0.922
rocA
Pyrroline-5-carboxylate dehydrogenase, RocA; Involved in the arginase pathway [catalytic activity: 1-pyrroline-5-carboxylate + NAD(+) + H(2)O = L- glutamate + NADH].
   
 0.916
glmS
Glucosamine-fructose-6-phosphate aminotransferase, GlmS; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.913
glnA3
Glutamine synthetase GlnA3; Involved in glutamine biosynthesis [catalytic activity: ATP + L-glutamate + NH(3) = ADP + glutamine + orthophosphate]; Belongs to the glutamine synthetase family.
    
 0.912
glnA1
Glutamine synthetase GlnA1; Involved in glutamine biosynthesis [catalytic activity: ATP + L-glutamate + NH(3) = ADP + glutamine + orthophosphate].
    
 0.912
glnA2
Glutamine synthetase GlnA2; Involved in glutamine biosynthesis [catalytic activity: ATP + L-glutamate + NH(3) = ADP + glutamine + orthophosphate]; Belongs to the glutamine synthetase family.
    
 0.912
murD
UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
    
 0.907
gltD
NADH-dependent glutamate synthase (small subunit) GltD; Probably involved in glutamate biosynthesis [catalytic activity: 2 L-glutamate + NAD(+) = L-glutamine + 2-oxoglutarate + NADH].
  
 
 0.906
Your Current Organism:
Mycobacterium marinum
NCBI taxonomy Id: 216594
Other names: M. marinum M, Mycobacterium marinum M, Mycobacterium marinum str. M, Mycobacterium marinum strain M
Server load: low (32%) [HD]