node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MMAR_1180 | MMAR_3099 | MMAR_1180 | MMAR_3099 | N-term fused in-frame with fatty acyl-AMP ligase FadD28_1; Synthesis of unknown polyketide. | Polyketide synthase and peptide synthetase; Production of unknown metabolite. this CDS encodes a single NRP and PKS module with domain structure: (KS, Ata, DH, ER, KR, ACP). | 0.999 |
MMAR_1180 | MMAR_3304 | MMAR_1180 | MMAR_3304 | N-term fused in-frame with fatty acyl-AMP ligase FadD28_1; Synthesis of unknown polyketide. | Conserved hypothetical protein. | 0.571 |
MMAR_1180 | coaE | MMAR_1180 | MMAR_2434 | N-term fused in-frame with fatty acyl-AMP ligase FadD28_1; Synthesis of unknown polyketide. | dephospho-CoA kinase CoaE; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.461 |
MMAR_1180 | dnaN | MMAR_1180 | MMAR_0002 | N-term fused in-frame with fatty acyl-AMP ligase FadD28_1; Synthesis of unknown polyketide. | DNA polymerase III (beta chain) DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...] | 0.487 |
MMAR_1180 | dnaN_1 | MMAR_1180 | MMAR_3926 | N-term fused in-frame with fatty acyl-AMP ligase FadD28_1; Synthesis of unknown polyketide. | Probably involved in phage genome replication. DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. this DNA polymerase also exhibits 3' to 5' exonuclease activity. the beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA [catalytic activity: N deoxynucleoside triphosphate = N diphosphate + {DNA}n]. | 0.487 |
MMAR_1180 | lppK | MMAR_1180 | MMAR_3092 | N-term fused in-frame with fatty acyl-AMP ligase FadD28_1; Synthesis of unknown polyketide. | Conserved lipoprotein, LppK. | 0.487 |
MMAR_1180 | polA | MMAR_1180 | MMAR_2432 | N-term fused in-frame with fatty acyl-AMP ligase FadD28_1; Synthesis of unknown polyketide. | DNA polymerase I PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.749 |
MMAR_1180 | rnhB | MMAR_1180 | MMAR_1806 | N-term fused in-frame with fatty acyl-AMP ligase FadD28_1; Synthesis of unknown polyketide. | Ribonuclease HII protein RnhB; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.765 |
MMAR_1180 | rplS | MMAR_1180 | MMAR_1804 | N-term fused in-frame with fatty acyl-AMP ligase FadD28_1; Synthesis of unknown polyketide. | 50S ribosomal protein L19 RplS; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.661 |
MMAR_3099 | MMAR_1180 | MMAR_3099 | MMAR_1180 | Polyketide synthase and peptide synthetase; Production of unknown metabolite. this CDS encodes a single NRP and PKS module with domain structure: (KS, Ata, DH, ER, KR, ACP). | N-term fused in-frame with fatty acyl-AMP ligase FadD28_1; Synthesis of unknown polyketide. | 0.999 |
MMAR_3099 | MMAR_3304 | MMAR_3099 | MMAR_3304 | Polyketide synthase and peptide synthetase; Production of unknown metabolite. this CDS encodes a single NRP and PKS module with domain structure: (KS, Ata, DH, ER, KR, ACP). | Conserved hypothetical protein. | 0.571 |
MMAR_3099 | coaE | MMAR_3099 | MMAR_2434 | Polyketide synthase and peptide synthetase; Production of unknown metabolite. this CDS encodes a single NRP and PKS module with domain structure: (KS, Ata, DH, ER, KR, ACP). | dephospho-CoA kinase CoaE; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.461 |
MMAR_3099 | dnaN | MMAR_3099 | MMAR_0002 | Polyketide synthase and peptide synthetase; Production of unknown metabolite. this CDS encodes a single NRP and PKS module with domain structure: (KS, Ata, DH, ER, KR, ACP). | DNA polymerase III (beta chain) DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...] | 0.487 |
MMAR_3099 | dnaN_1 | MMAR_3099 | MMAR_3926 | Polyketide synthase and peptide synthetase; Production of unknown metabolite. this CDS encodes a single NRP and PKS module with domain structure: (KS, Ata, DH, ER, KR, ACP). | Probably involved in phage genome replication. DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. this DNA polymerase also exhibits 3' to 5' exonuclease activity. the beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA [catalytic activity: N deoxynucleoside triphosphate = N diphosphate + {DNA}n]. | 0.487 |
MMAR_3099 | lppK | MMAR_3099 | MMAR_3092 | Polyketide synthase and peptide synthetase; Production of unknown metabolite. this CDS encodes a single NRP and PKS module with domain structure: (KS, Ata, DH, ER, KR, ACP). | Conserved lipoprotein, LppK. | 0.487 |
MMAR_3099 | polA | MMAR_3099 | MMAR_2432 | Polyketide synthase and peptide synthetase; Production of unknown metabolite. this CDS encodes a single NRP and PKS module with domain structure: (KS, Ata, DH, ER, KR, ACP). | DNA polymerase I PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.749 |
MMAR_3099 | rnhB | MMAR_3099 | MMAR_1806 | Polyketide synthase and peptide synthetase; Production of unknown metabolite. this CDS encodes a single NRP and PKS module with domain structure: (KS, Ata, DH, ER, KR, ACP). | Ribonuclease HII protein RnhB; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.765 |
MMAR_3099 | rplS | MMAR_3099 | MMAR_1804 | Polyketide synthase and peptide synthetase; Production of unknown metabolite. this CDS encodes a single NRP and PKS module with domain structure: (KS, Ata, DH, ER, KR, ACP). | 50S ribosomal protein L19 RplS; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.661 |
MMAR_3304 | MMAR_1180 | MMAR_3304 | MMAR_1180 | Conserved hypothetical protein. | N-term fused in-frame with fatty acyl-AMP ligase FadD28_1; Synthesis of unknown polyketide. | 0.571 |
MMAR_3304 | MMAR_3099 | MMAR_3304 | MMAR_3099 | Conserved hypothetical protein. | Polyketide synthase and peptide synthetase; Production of unknown metabolite. this CDS encodes a single NRP and PKS module with domain structure: (KS, Ata, DH, ER, KR, ACP). | 0.571 |