STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mqoMalate:quinone oxidoreductase Mqo; Involved in tricarboxylic acid cycle [catalytic activity: (S)-malate + acceptor = oxaloacetate + reduced acceptor]. (493 aa)    
Predicted Functional Partners:
fum
Fumarase Fum; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
    
 0.977
glcB
Malate synthase G GlcB; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
     
 0.973
gltA1
Citrate synthase I GltA1; Involved in tricarboxylic acid cycle (krebs cycle) [catalytic activity: citrate + CoA = acetyl-CoA + H2O + oxaloacetate]; Belongs to the citrate synthase family.
  
 
 0.967
gltA2
Citrate synthase I GltA2; Involved in tricarboxylic acid cycle (krebs cycle) [catalytic activity: citrate + CoA = acetyl-CoA + H2O + oxaloacetate]; Belongs to the citrate synthase family.
  
 
 0.967
mdh
Malate dehydrogenase Mdh; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
   
 0.962
citA
Citrate synthase II CitA; Involved in tricarboxylic acid cycle (krebs cycle) [catalytic activity: citrate + CoA = acetyl-CoA + H2O + oxaloacetate]; Belongs to the citrate synthase family.
  
 
 0.942
pca
Pyruvate carboxylase Pca; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 
 0.934
ppc
Phosphoenolpyruvate carboxylase, Ppc; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.
    
 0.926
pckA
Iron-regulated phosphoenolpyruvate carboxykinase [GTP] PckA; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
   
 
 0.924
mez
[NAD] dependent malate oxidoreductase Mez; Catalizes the oxidative decarboxylation of malate into pyruvate, important for a wide range of metabolic pathways [catalytic activity: (S)-malate + NAD(+) = pyruvate + CO(2) + NADH].
  
 
 0.915
Your Current Organism:
Mycobacterium marinum
NCBI taxonomy Id: 216594
Other names: M. marinum M, Mycobacterium marinum M, Mycobacterium marinum str. M, Mycobacterium marinum strain M
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