node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MMAR_1936 | dapA | MMAR_1936 | MMAR_1962 | Conserved hypothetical protein. | Dihydrodipicolinate synthase DapA; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.900 |
MMAR_1936 | dapA_1 | MMAR_1936 | MMAR_2154 | Conserved hypothetical protein. | Dihydrodipicolinate synthase DapA_1; Involved in biosynthesis of diaminopimelate and lysine from aspartate semialdehyde (at the first step) [catalytic activity: l-aspartate 4-semialdehyde + pyruvate = dihydrodipicolinate + 2 H(2)O]; Belongs to the DapA family. | 0.900 |
MMAR_1936 | dapB | MMAR_1936 | MMAR_1938 | Conserved hypothetical protein. | Dihydrodipicolinate reductase DapB; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. | 0.901 |
MMAR_1936 | dapD | MMAR_1936 | MMAR_4236 | Conserved hypothetical protein. | Transferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. | 0.900 |
MMAR_1939 | MMAR_1940 | MMAR_1939 | MMAR_1940 | Conserved hypothetical secreted protein. | Conserved hypothetical protein. | 0.826 |
MMAR_1939 | dapB | MMAR_1939 | MMAR_1938 | Conserved hypothetical secreted protein. | Dihydrodipicolinate reductase DapB; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. | 0.893 |
MMAR_1940 | MMAR_1939 | MMAR_1940 | MMAR_1939 | Conserved hypothetical protein. | Conserved hypothetical secreted protein. | 0.826 |
MMAR_1940 | dapB | MMAR_1940 | MMAR_1938 | Conserved hypothetical protein. | Dihydrodipicolinate reductase DapB; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. | 0.810 |
asd | ask | MMAR_5221 | MMAR_5222 | Aspartate-semialdehyde dehydrogenase Asd; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Aspartate kinase Ask; Involved at the first step in the common biosynthetic pathway leading from asp to the cell wall precursor meso-diaminopimelate, to lys, to met, to ile and to the[catalytic activity: ATP + l-aspartate = ADP + 4- phospho-L-aspartate]. possibly acts in tetramer configuration, tetramer consisting of two alpha (catalytic activity) and two beta (function not known) chains; Belongs to the aspartokinase family. | 0.999 |
asd | dapA | MMAR_5221 | MMAR_1962 | Aspartate-semialdehyde dehydrogenase Asd; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Dihydrodipicolinate synthase DapA; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.983 |
asd | dapA_1 | MMAR_5221 | MMAR_2154 | Aspartate-semialdehyde dehydrogenase Asd; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Dihydrodipicolinate synthase DapA_1; Involved in biosynthesis of diaminopimelate and lysine from aspartate semialdehyde (at the first step) [catalytic activity: l-aspartate 4-semialdehyde + pyruvate = dihydrodipicolinate + 2 H(2)O]; Belongs to the DapA family. | 0.977 |
asd | dapB | MMAR_5221 | MMAR_1938 | Aspartate-semialdehyde dehydrogenase Asd; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Dihydrodipicolinate reductase DapB; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. | 0.936 |
asd | dapD | MMAR_5221 | MMAR_4236 | Aspartate-semialdehyde dehydrogenase Asd; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Transferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. | 0.799 |
asd | dapF | MMAR_5221 | MMAR_1987 | Aspartate-semialdehyde dehydrogenase Asd; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Diaminopimelate epimerase DapF; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.929 |
asd | lysA | MMAR_5221 | MMAR_4104 | Aspartate-semialdehyde dehydrogenase Asd; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Diaminopimelate decarboxylase LysA; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.911 |
ask | asd | MMAR_5222 | MMAR_5221 | Aspartate kinase Ask; Involved at the first step in the common biosynthetic pathway leading from asp to the cell wall precursor meso-diaminopimelate, to lys, to met, to ile and to the[catalytic activity: ATP + l-aspartate = ADP + 4- phospho-L-aspartate]. possibly acts in tetramer configuration, tetramer consisting of two alpha (catalytic activity) and two beta (function not known) chains; Belongs to the aspartokinase family. | Aspartate-semialdehyde dehydrogenase Asd; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.999 |
ask | dapA | MMAR_5222 | MMAR_1962 | Aspartate kinase Ask; Involved at the first step in the common biosynthetic pathway leading from asp to the cell wall precursor meso-diaminopimelate, to lys, to met, to ile and to the[catalytic activity: ATP + l-aspartate = ADP + 4- phospho-L-aspartate]. possibly acts in tetramer configuration, tetramer consisting of two alpha (catalytic activity) and two beta (function not known) chains; Belongs to the aspartokinase family. | Dihydrodipicolinate synthase DapA; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.847 |
ask | dapA_1 | MMAR_5222 | MMAR_2154 | Aspartate kinase Ask; Involved at the first step in the common biosynthetic pathway leading from asp to the cell wall precursor meso-diaminopimelate, to lys, to met, to ile and to the[catalytic activity: ATP + l-aspartate = ADP + 4- phospho-L-aspartate]. possibly acts in tetramer configuration, tetramer consisting of two alpha (catalytic activity) and two beta (function not known) chains; Belongs to the aspartokinase family. | Dihydrodipicolinate synthase DapA_1; Involved in biosynthesis of diaminopimelate and lysine from aspartate semialdehyde (at the first step) [catalytic activity: l-aspartate 4-semialdehyde + pyruvate = dihydrodipicolinate + 2 H(2)O]; Belongs to the DapA family. | 0.772 |
ask | dapB | MMAR_5222 | MMAR_1938 | Aspartate kinase Ask; Involved at the first step in the common biosynthetic pathway leading from asp to the cell wall precursor meso-diaminopimelate, to lys, to met, to ile and to the[catalytic activity: ATP + l-aspartate = ADP + 4- phospho-L-aspartate]. possibly acts in tetramer configuration, tetramer consisting of two alpha (catalytic activity) and two beta (function not known) chains; Belongs to the aspartokinase family. | Dihydrodipicolinate reductase DapB; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. | 0.906 |
ask | dapD | MMAR_5222 | MMAR_4236 | Aspartate kinase Ask; Involved at the first step in the common biosynthetic pathway leading from asp to the cell wall precursor meso-diaminopimelate, to lys, to met, to ile and to the[catalytic activity: ATP + l-aspartate = ADP + 4- phospho-L-aspartate]. possibly acts in tetramer configuration, tetramer consisting of two alpha (catalytic activity) and two beta (function not known) chains; Belongs to the aspartokinase family. | Transferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. | 0.840 |