STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gabT4-aminobutyrate aminotransferase GabT; Involved in 4-aminobutyrate (GabA) degradation pathway [catalytic activity: 4-aminobutanoate + 2- oxoglutarate = succinate semialdehyde + L-glutamate]; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (446 aa)    
Predicted Functional Partners:
yajC
Conserved membrane protein secretion factor YajC; Thought to be involved in secretion apparatus.
     
 0.968
gadB
Glutamate decarboxylase, GadB; Catalyzes the production of GabA [catalytic activity: L-glutamate = 4-aminobutanoate + CO(2)]; Belongs to the group II decarboxylase family.
  
 0.947
MMAR_0359
Aldehyde dehydrogenase (NAD+) dependent; Function unknown, probably involved in cellular metabolism [catalytic activity: an aldehyde + NAD+ + H2O = an acid + NADH]; Belongs to the aldehyde dehydrogenase family.
  
 0.934
MMAR_0472
Aldehyde dehydrogenase; Thought to oxidize a wide variety of aliphatic and aromatic aldehydes; Belongs to the aldehyde dehydrogenase family.
 
 0.934
gabD1
Succinate-semialdehyde dehydrogenase [NADP+] dependent (SsdH) GabD1; Involved in 4-aminobutyrate (GabA) degradation pathway [catalytic activity: succinate semialdehyde + NAD(P)(+) + H(2)O = succinate + NAD(P)H].
 
 0.934
mmsA
Methylmalonate semialdehyde dehydrogenase, MmsA; Plays a role in valine and pyrimidine metabolism. binds fatty acyl-CoA [catalytic activity: 2-methyl-3- oxopropanoate + CoA + NAD+ = propanoyl-CoA + CO2 + NADH].
  
 0.934
pcd
Piperideine-6-carboxilic acid dehydrogenase Pcd; Involved in L-alpha-aminoadipic acid (L-AAA) biosynthesis (in the second step; the first step is promoted by Lat enzyme; Belongs to the aldehyde dehydrogenase family.
  
 0.934
gabD2
Succinate-semialdehyde dehydrogenase [NADP+] dependent (SsdH) GabD2; Involved in 4-aminobutyrate (GabA) degradation pathway [catalytic activity: succinate semialdehyde + NAD(P)(+) + H(2)O = succinate + NAD(P)H]; Belongs to the aldehyde dehydrogenase family.
  
 0.934
MMAR_2875
Aldehyde dehydrogenase; Thought to oxidize a wide variety of aliphatic and aromatic aldehydes.
 
 0.934
MMAR_3965
NAD-dependent aldehyde dehydrogenase; Thought to oxidize a wide variety of aliphatic and aromatic aldehydes; Belongs to the aldehyde dehydrogenase family.
 
 0.934
Your Current Organism:
Mycobacterium marinum
NCBI taxonomy Id: 216594
Other names: M. marinum M, Mycobacterium marinum M, Mycobacterium marinum str. M, Mycobacterium marinum strain M
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