STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ureBUrease beta subunit UreB; Involved in the conversion of UreA to NH3 [catalytic activity: UreA + H2O = CO2 + 2 NH3]; Belongs to the urease beta subunit family. (103 aa)    
Predicted Functional Partners:
ureA
Urease gamma subunit UreA; Involved in the conversion of UreA to NH3 [catalytic activity: UreA + H2O = CO2 + 2 NH3]; Belongs to the urease gamma subunit family.
 0.999
ureC
Urease alpha subunit UreC; Involved in the conversion of UreA to NH3 [catalytic activity: UreA + H2O = CO2 + 2 NH3]; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
 0.999
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
  
 0.998
ureD
UreD is involved in activation of the urease enzyme via the UreD-UreF-UreG-urease complex and is required for urease nickel metallocenter assembly.
  
 
 0.987
ureF
Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.984
alc
Allantoicase Alc; These proteins allow the use of purines as secondary nitrogen sources in nitrogen-limiting conditions through the reaction: allantoate + H(2)0 = (-)- ureidoglycolate + UreA; Belongs to the allantoicase family.
    
  0.906
MMAR_2721
Conserved hypothetical protein; Function unknown but domain identity suggests possibly involved in aromatic compound catabolism.
       0.844
ybeY
Conserved hypothetical metal-dependent hydrolase; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
      
 0.691
hypB
Nickel cation-binding GTPase, HypB; Involved in regulation of expression and maturation of urease and hydrogenase.
  
  
 0.632
echA21
enoyl-CoA hydratase, EchA21; Function unknown; probably involved in lipid metabolism.
      
 0.531
Your Current Organism:
Mycobacterium marinum
NCBI taxonomy Id: 216594
Other names: M. marinum M, Mycobacterium marinum M, Mycobacterium marinum str. M, Mycobacterium marinum strain M
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.