STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rsbURegulator of sigma subunit, anti-anti-sigma factor RsbU; May be involved in regulation of SigG. (653 aa)    
Predicted Functional Partners:
MMAR_0738
Two-component sensor and regulator.
 
 
0.999
MMAR_5186
Sensor-component of a two-component regulator.
 
 
0.999
MMAR_5181
Anti-anti-sigma regulatory factor; Function unknown; potential role in regulation of transcription; Belongs to the anti-sigma-factor antagonist family.
 
 
 0.957
fbiC
F420 biosynthesis protein FbiC; Essential for coenzyme F420 production: participates in a portion of the F420 biosynthetic pathway between pyrimidinedione and fo (biosynthesis intermediate), before the deazaflavin ring is formed.
  
  
 0.953
MMAR_1264
Two-component system membrane associated sensor kinase.
 
  
 0.952
MMAR_5182
Anti-anti-sigma regulatory factor; Function unknown; potential role in regulation of transcription.
 
 
 0.952
MMAR_5183
Conserved hypothetical protein; Function unknown; contains an anti-anti-sigma regulatory factor domain. may have a role in a signal transduction mechanism.
 
 
 0.951
sigF
The sigma factor is an initiation factor that promotes attachment of the RNA polymerase to specific initiation sites and then is released. thought to be involved in survival and proliferation in lung granulomas during infection. thought to be involved in virulence and persistence processes. modulates expression of the 16 kDa alpha-crystallin homologue. negatively regulated by RsbW/UsfX.
 
 
 0.948
MMAR_0214
Conserved hypothetical protein; Function unknown. domain identity suggests anti- anti-sigma regulatory factor; Belongs to the anti-sigma-factor antagonist family.
 
 
 0.947
MMAR_2800
Conserved hypothetical protein; Belongs to the anti-sigma-factor antagonist family.
 
 
 0.947
Your Current Organism:
Mycobacterium marinum
NCBI taxonomy Id: 216594
Other names: M. marinum M, Mycobacterium marinum M, Mycobacterium marinum str. M, Mycobacterium marinum strain M
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.