STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
enoEnolase Eno; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (428 aa)    
Predicted Functional Partners:
pgk
Phosphoglycerate kinase Pgk; Involved in the second phase of glycolysis (second step) [catalytic activity : ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate]; Belongs to the phosphoglycerate kinase family.
 
 
 0.996
pykA
Pyruvate kinase PykA; Produces phosphoenol pyruvate in glycolysis [catalytic activity : ATP + pyruvate = ADP + phosphoenolpyruvate]; Belongs to the pyruvate kinase family.
 
 0.994
gap
Glyceraldehyde 3-phosphate dehydrogenase Gap; Involved in second phase of glycolysis (first step) [catalytic activity: D-glyceraldehyde 3-phosphate + phosphate + NAD(+) = 3-phospho-D-glyceroyl phosphate + NADH.]; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 
 
 0.989
tpi
Triosephosphate isomerase Tpi; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 
 0.988
pgi
Glucose-6-phosphate isomerase Pgi; Involved in glycolysis and in gluconeogenesis [catalytic activity: d-glucose 6-phosphate = D-fructose 6- phosphate]; Belongs to the GPI family.
  
 0.986
gpm1
Phosphoglycerate mutase 1 Gpm1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
 0.983
fba
Fructose-bisphosphate aldolase, Fba; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
 0.982
tal
Transaldolase Tal; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
   
 0.963
tkt
Transketolase Tkt; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
 
 0.962
gltB
Ferredoxin-dependent glutamate synthase [NADPH] (large subunit) GltB; Probably involved in glutamate biosynthesis [catalytic activity: 2 L-glutamate + NADP(+) = L-glutamine + 2-oxoglutarate + NADPH].
  
  
 0.941
Your Current Organism:
Mycobacterium marinum
NCBI taxonomy Id: 216594
Other names: M. marinum M, Mycobacterium marinum M, Mycobacterium marinum str. M, Mycobacterium marinum strain M
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