STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pheAPrephenate dehydratase PheA; Involved in L-phenylalanine biosynthesis [catalytic activity: prephenate = phenylpyruvate + H(2)O + CO(2)]. (315 aa)    
Predicted Functional Partners:
tyrA
Prephenate dehydrogenase TyrA; Involved in tyrosine biosynthesis [catalytic activity: prephenate + NAD(+) = 4-hydroxyphenylpyruvate + CO(2) + NADH].
 
 0.989
MMAR_4555
Conserved hypothetical protein.
  
 
 0.932
MMAR_2773
Conserved secreted protein; Catalyzes the Claisen rearrangement of chorismate to prephenate.
  
 
 0.922
hisC1
Histidinol-phosphate aminotransferase HisC1; Histidine biosynthesis (eighth step) [catalytic activity : L-histidinol-phosphate + 2-oxoglutarate = 3- (imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate]; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
 
 0.917
cobC
Aminotransferase CobC; Involved in cobalamin biosynthesis.
  
 
 0.917
hisC2
Histidinol-phosphate aminotransferase HisC2; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.917
trpD
Anthranilate phosphoribosyltransferase TrpD; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
  
 0.895
trpA
Tryptophan synthase, alpha subunit TrpA; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
   
 0.875
MMAR_5389
Phosphoglycerate mutase; Thought to be involved in glycolisis and perhaps glycogen metabolism [catalytic activity: 3- phosphoglycerate = 2-phosphoglycerate]; Belongs to the phosphoglycerate mutase family.
     
 0.875
aroE
Shikimate 5-dehydrogenase AroE; Possibly involved at the fourth step in the biosynthesis of chorismate within the biosynthesis of aromatic amino acids (the shikimate pathway) [catalytic activity: shikimate + NADP(+) = 5-dehydroshikimate + NADPH]; Belongs to the shikimate dehydrogenase family.
 
   
 0.874
Your Current Organism:
Mycobacterium marinum
NCBI taxonomy Id: 216594
Other names: M. marinum M, Mycobacterium marinum M, Mycobacterium marinum str. M, Mycobacterium marinum strain M
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