STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
lpoBPutative lipoprotein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b). Belongs to the LpoB family. (193 aa)    
Predicted Functional Partners:
ECA1810
Similar to Yersinia pestis putative lipoprotein ypo1612 SWALL:Q8ZFS6 (EMBL:AJ414149) (129 aa) fasta scores: E(): 1e-15, 44.53% id in 119 aa, and to Shigella flexneri orf, conserved hypothetical protein ycfl or sf1108 SWALL:AAN42726 (EMBL:AE015138) (125 aa) fasta scores: E(): 1.5e-14, 38.88% id in 126 aa.
 
  
 0.959
mrcB
Penicillin-binding protein 1b; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
  
 
 
 0.886
ftsN
Cell division protein; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases.
  
   
 0.831
rof
Modulator of rho-dependent transcription termination; Similar to Escherichia coli, and Shigella flexneri Rof protein or b0189 or sf0179 SWALL:ROF_ECOLI (SWALL:P52098) (84 aa) fasta scores: E(): 3.4e-22, 70.23% id in 84 aa, and to Salmonella typhimurium modulator of rho-dependent transcription termination Rof or stm0237 SWALL:Q8ZRN4 (EMBL:AE008706) (86 aa) fasta scores: E(): 2.9e-20, 66.27% id in 86 aa.
  
   
 0.830
thiK
Conserved hypothetical protein; Catalyzes the phosphorylation of thiamine to thiamine phosphate.
 
  
 0.800
ECA1809
Similar to Yersinia pestis hypothetical protein ypo1611 ypo1611 or y1770 SWALL:Q8ZFS7 (EMBL:AJ414149) (117 aa) fasta scores: E(): 3.7e-38, 86.84% id in 114 aa, and to Salmonella typhimurium, and Salmonella typhi hypothetical protein ycff ycff or stm1205 or sty1245 SWALL:Q8XER7 (EMBL:AE008752) (119 aa) fasta scores: E(): 9.5e-38, 83.47% id in 115 aa.
  
  
 0.779
holD
DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.
  
     0.773
helD
Helicase IV; Similar to Escherichia coli helicase IV HelD or b0962 SWALL:HELD_ECOLI (SWALL:P15038) (684 aa) fasta scores: E(): 1.6e-197, 69.29% id in 684 aa.
  
     0.771
smp
Putative membrane protein; Similar to Escherichia coli, and Shigella flexneri protein Smp precursor Smp or b4387 or sf4419 SWALL:SMP_ECOLI (SWALL:P18838) (214 aa) fasta scores: E(): 3.9e-52, 65.72% id in 213 aa.
  
     0.770
ompN
Similar to Escherichia coli outer membrane protein N precursor OmpN or b1377 SWALL:OMPN_ECOLI (SWALL:P77747) (377 aa) fasta scores: E(): 1.1e-76, 53.86% id in 388 aa.
  
     0.770
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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