STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA1841Similar to Escherichia coli hypothetical protein ydiv or b1707 SWALL:YDIV_ECOLI (SWALL:P76204) (237 aa) fasta scores: E(): 3.5e-23, 36.17% id in 235 aa, and to Shigella flexneri orf, conserved hypothetical protein ydiv or sf1524 SWALL:AAN43114 (EMBL:AE015175) (237 aa) fasta scores: E(): 3.1e-22, 35.74% id in 235 aa. (241 aa)    
Predicted Functional Partners:
ECA3886
Putative membrane protein; Similar to the C-terminal region of many including Pseudomonas aeruginosa hypothetical protein Pa2870 SWALL:Q9HZX6 (EMBL:AE004713) (525 aa) fasta scores: E(): 1.9e-17, 39.39% id in 165 aa, and to Shewanella oneidensis ggdef domain protein so4457 SWALL:AAN57422 (EMBL:AE015878) (485 aa) fasta scores: E(): 2.1e-17, 39.03% id in 187 aa.
  
 
 0.791
wecH
Putative membrane protein; Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units.
  
     0.767
ECA1991
Similar to Yersinia pestis hypothetical protein ypo2340 or y1992 SWALL:Q8ZE44 (EMBL:AJ414152) (256 aa) fasta scores: E(): 5.7e-69, 73.93% id in 234 aa, and to Shigella dysenteriae YcjI SWALL:Q9LA26 (EMBL:AF153317) (262 aa) fasta scores: E(): 1.4e-67, 70.08% id in 234 aa.
  
     0.762
ECA3270
Putative exported protein; Similar to Rhizobium meliloti hypothetical protein r00959 or smc00038 SWALL:Q92KJ3 (EMBL:AL591785) (772 aa) fasta scores: E(): 1e-48, 35.35% id in 461 aa, and to Xanthomonas campestris c-di-gmp phosphodiesterase A PdeA or xcc1865 SWALL:Q8P9J8 (EMBL:AE012289) (726 aa) fasta scores: E(): 1.1e-41, 31.81% id in 462 aa.
  
  
 0.752
flhD
Flagellar transcriptional activator; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family.
    
 
 0.749
flk
Cell division protein; Acts as a regulator of flagellar gene expression by modulating the protein level of the anti sigma factor FlgM upon sensing ring completion or hook elongation. Flk could inhibit FlgM secretion by acting as a braking system for the flagellar-associated type III secretion system.
  
     0.742
arcB
Similar to Escherichia coli, and Shigella flexneri aerobic respiration control sensor protein ArcB or b3210 or sf3250 SWALL:ARCB_ECOLI (SWALL:P22763) (778 aa) fasta scores: E(): 8.6e-180, 75.88% id in 788 aa, and to Yersinia pestis aerobic respiration control sensor/response regulatory protein ArcB SWALL:Q8ZB69 (EMBL:AJ414157) (778 aa) fasta scores: E(): 3.6e-190, 80.71% id in 788 aa.
  
 
 0.733
ECA2388
Similar to Yersinia pestis putative membrane protein ypo1755 or y2554 SWALL:AAM86109 (EMBL:AJ414150) (153 aa) fasta scores: E(): 3e-41, 73.02% id in 152 aa, and to Escherichia coli, and Escherichia coli O6 hypothetical protein yobd or b1820 or c2227 SWALL:YOBD_ECOLI (SWALL:P76263) (152 aa) fasta scores: E(): 8.8e-33, 57.89% id in 152 aa.
  
     0.707
rpfA
Two-component sensor kinase and response regulator; Similar to Pectobacterium carotovorum subsp. carotovorum sensor/regulator protein RpfA SWALL:O08235 (EMBL:U62023) (929 aa) fasta scores: E(): 0, 92.88% id in 928 aa, and to Pectobacterium carotovorum subsp. carotovorum sensory kinase ExpS SWALL:O32556 (EMBL:Y13670) (928 aa) fasta scores: E(): 0, 95.36% id in 928 aa.
  
  
 0.697
mtlR
Mannitol operon repressor; Similar to Escherichia coli, and Escherichia coli O6 mannitol operon repressor MtlR or b3601 or c4418 SWALL:MTLR_ECOLI (SWALL:P36563) (195 aa) fasta scores: E(): 2.6e-47, 74.15% id in 178 aa.
  
     0.694
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.