| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| crcB | ybaX | SBG_0538 | SBG_0400 | Putative membrane protein. | Conserved hypothetical protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.531 |
| folE | nrdG | SBG_2005 | SBG_3874 | GTP cyclohydrolase I. | Conserved hypothetical protein, VagC-related (pseudogene); Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 0.442 |
| folE | queD | SBG_2005 | SBG_2564 | GTP cyclohydrolase I. | Putative 6-pyruvoyl tetrahydrobiopterin synthase. | 0.986 |
| folE | queE | SBG_2005 | SBG_2566 | GTP cyclohydrolase I. | Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.908 |
| folE | queF_2 | SBG_2005 | SBG_2583 | GTP cyclohydrolase I. | Conserved hypothetical protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.859 |
| folE | ybaX | SBG_2005 | SBG_0400 | GTP cyclohydrolase I. | Conserved hypothetical protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.852 |
| folE | yjeS | SBG_2005 | SBG_3799 | GTP cyclohydrolase I. | Putative 4Fe-4S binding protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. | 0.401 |
| nrdG | folE | SBG_3874 | SBG_2005 | Conserved hypothetical protein, VagC-related (pseudogene); Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | GTP cyclohydrolase I. | 0.442 |
| nrdG | queD | SBG_3874 | SBG_2564 | Conserved hypothetical protein, VagC-related (pseudogene); Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | Putative 6-pyruvoyl tetrahydrobiopterin synthase. | 0.758 |
| nrdG | queF_2 | SBG_3874 | SBG_2583 | Conserved hypothetical protein, VagC-related (pseudogene); Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | Conserved hypothetical protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.805 |
| nrdG | ybaX | SBG_3874 | SBG_0400 | Conserved hypothetical protein, VagC-related (pseudogene); Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | Conserved hypothetical protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.623 |
| queA | queE | SBG_0360 | SBG_2566 | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.527 |
| queA | queF_2 | SBG_0360 | SBG_2583 | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Conserved hypothetical protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.872 |
| queA | tgt | SBG_0360 | SBG_0361 | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Queuine tRNA-ribosyltransferase; tRNA-guanine transglycosylase. | 0.976 |
| queA | ybaX | SBG_0360 | SBG_0400 | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Conserved hypothetical protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.862 |
| queA | yjeS | SBG_0360 | SBG_3799 | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Putative 4Fe-4S binding protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. | 0.931 |
| queD | folE | SBG_2564 | SBG_2005 | Putative 6-pyruvoyl tetrahydrobiopterin synthase. | GTP cyclohydrolase I. | 0.986 |
| queD | nrdG | SBG_2564 | SBG_3874 | Putative 6-pyruvoyl tetrahydrobiopterin synthase. | Conserved hypothetical protein, VagC-related (pseudogene); Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 0.758 |
| queD | queE | SBG_2564 | SBG_2566 | Putative 6-pyruvoyl tetrahydrobiopterin synthase. | Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.996 |
| queD | queF_2 | SBG_2564 | SBG_2583 | Putative 6-pyruvoyl tetrahydrobiopterin synthase. | Conserved hypothetical protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.855 |