| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SBG_2964 | lutR | SBG_2964 | SBG_2969 | Conserved hypothetical protein. | Putative GntR-family transcriptional regulator; Transcriptional repressor that controls expression of the genes required for the catabolism of sialic acids. | 0.874 |
| SBG_2964 | nanA | SBG_2964 | SBG_2968 | Conserved hypothetical protein. | N-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate. | 0.844 |
| SBG_2964 | nanE2 | SBG_2964 | SBG_2966 | Conserved hypothetical protein. | Conserved hypothetical protein; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). | 0.980 |
| SBG_2964 | nanK | SBG_2964 | SBG_2965 | Conserved hypothetical protein. | Putative kinase; Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P; Belongs to the ROK (NagC/XylR) family. NanK subfamily. | 0.980 |
| SBG_2964 | nanT | SBG_2964 | SBG_2967 | Conserved hypothetical protein. | Putative sialic acid transporter. | 0.946 |
| citF | citX | SBG_0529 | SBG_0528 | Citrate lyase alpha chain. | Conserved hypothetical protein. | 0.995 |
| citF | nanA | SBG_0529 | SBG_2968 | Citrate lyase alpha chain. | N-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate. | 0.749 |
| citX | citF | SBG_0528 | SBG_0529 | Conserved hypothetical protein. | Citrate lyase alpha chain. | 0.995 |
| citX | nanA | SBG_0528 | SBG_2968 | Conserved hypothetical protein. | N-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate. | 0.684 |
| dapB | nanA | SBG_0048 | SBG_2968 | Ribonucleoside hydrolase 3 (remnant); Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | N-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate. | 0.796 |
| hpaX | nanA | SBG_0953 | SBG_2968 | Putative 4-hydroxyphenylacetate permease. | N-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate. | 0.628 |
| lutR | SBG_2964 | SBG_2969 | SBG_2964 | Putative GntR-family transcriptional regulator; Transcriptional repressor that controls expression of the genes required for the catabolism of sialic acids. | Conserved hypothetical protein. | 0.874 |
| lutR | nanA | SBG_2969 | SBG_2968 | Putative GntR-family transcriptional regulator; Transcriptional repressor that controls expression of the genes required for the catabolism of sialic acids. | N-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate. | 0.929 |
| lutR | nanE2 | SBG_2969 | SBG_2966 | Putative GntR-family transcriptional regulator; Transcriptional repressor that controls expression of the genes required for the catabolism of sialic acids. | Conserved hypothetical protein; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). | 0.894 |
| lutR | nanK | SBG_2969 | SBG_2965 | Putative GntR-family transcriptional regulator; Transcriptional repressor that controls expression of the genes required for the catabolism of sialic acids. | Putative kinase; Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P; Belongs to the ROK (NagC/XylR) family. NanK subfamily. | 0.759 |
| lutR | nanT | SBG_2969 | SBG_2967 | Putative GntR-family transcriptional regulator; Transcriptional repressor that controls expression of the genes required for the catabolism of sialic acids. | Putative sialic acid transporter. | 0.939 |
| nanA | SBG_2964 | SBG_2968 | SBG_2964 | N-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate. | Conserved hypothetical protein. | 0.844 |
| nanA | citF | SBG_2968 | SBG_0529 | N-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate. | Citrate lyase alpha chain. | 0.749 |
| nanA | citX | SBG_2968 | SBG_0528 | N-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate. | Conserved hypothetical protein. | 0.684 |
| nanA | dapB | SBG_2968 | SBG_0048 | N-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate. | Ribonucleoside hydrolase 3 (remnant); Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.796 |