| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| STY2566 | rraB | SBG_2122 | SBG_3890 | Conserved hypothetical protein. | Conserved hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.749 |
| STY2566 | rseA | SBG_2122 | SBG_2357 | Conserved hypothetical protein. | sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...] | 0.627 |
| STY2566 | seqA | SBG_2122 | SBG_0587 | Conserved hypothetical protein. | seqA protein. | 0.742 |
| STY2566 | slyX | SBG_2122 | SBG_3063 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.635 |
| STY2566 | syd | SBG_2122 | SBG_2582 | Conserved hypothetical protein. | Syd protein; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family. | 0.748 |
| STY2566 | yciS | SBG_2122 | SBG_1572 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.593 |
| STY2566 | yihI | SBG_2122 | SBG_3527 | Conserved hypothetical protein. | Conserved hypothetical protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family. | 0.778 |
| corE | rseA | SBG_2394 | SBG_2357 | Putative membrane protein. | sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...] | 0.552 |
| corE | seqA | SBG_2394 | SBG_0587 | Putative membrane protein. | seqA protein. | 0.494 |
| corE | slyX | SBG_2394 | SBG_3063 | Putative membrane protein. | Conserved hypothetical protein. | 0.699 |
| corE | yciS | SBG_2394 | SBG_1572 | Putative membrane protein. | Conserved hypothetical protein. | 0.567 |
| corE | yqaB | SBG_2394 | SBG_2445 | Putative membrane protein. | Conserved hypothetical protein. | 0.829 |
| rraB | STY2566 | SBG_3890 | SBG_2122 | Conserved hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | Conserved hypothetical protein. | 0.749 |
| rraB | rseA | SBG_3890 | SBG_2357 | Conserved hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...] | 0.649 |
| rraB | seqA | SBG_3890 | SBG_0587 | Conserved hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | seqA protein. | 0.757 |
| rraB | slyX | SBG_3890 | SBG_3063 | Conserved hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | Conserved hypothetical protein. | 0.661 |
| rraB | syd | SBG_3890 | SBG_2582 | Conserved hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | Syd protein; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family. | 0.757 |
| rraB | yciS | SBG_3890 | SBG_1572 | Conserved hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | Conserved hypothetical protein. | 0.681 |
| rraB | yihI | SBG_3890 | SBG_3527 | Conserved hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | Conserved hypothetical protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family. | 0.738 |
| rseA | STY2566 | SBG_2357 | SBG_2122 | sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...] | Conserved hypothetical protein. | 0.627 |