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ileS protein (Chlamydophila abortus) - STRING interaction network
"ileS" - Isoleucine--tRNA ligase in Chlamydophila abortus
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query proteins and first shell of interactors
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
ileSIsoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as ’pretransfer’ editing and involves the hydrolysis of activated Val-AMP. The other activity is designated ’posttransfer’ editing and involves deacylation of mischarged Val-tRNA(Ile); Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily (1043 aa)    
Predicted Functional Partners:
pheT
Phenylalanine--tRNA ligase beta subunit; Similar to Chlamydia pneumoniae phenylalanyl-tRNA synthetase beta chain PheT or cpn0594 or cp0154 SWALL-SYFB_CHLPN (SWALL-Q9Z7W0) (792 aa) fasta scores- E()- 1e-183, 59.11% id in 795 aa, and to Escherichia coli phenylalanyl-tRNA synthetase beta chain PheT or b1713 SWALL-SYFB_ECOLI (SWALL-P07395) (795 aa) fasta scores- E()- 1e-46, 27.1% id in 808 aa (794 aa)
   
 
  0.962
leuS
Leucine--tRNA ligase; Similar to Bacillus subtilis leucyl-tRNA synthetase LeuS or bsu30320 SWALL-SYL_BACSU (SWALL-P36430) (804 aa) fasta scores- E()- 1.4e-140, 50.89% id in 835 aa, and to Chlamydophila caviae leucyl-trna synthetase LeuS or cca00612 SWALL-SYL_CHLCV (SWALL-Q822R7) (820 aa) fasta scores- E()- 0, 89.51% id in 820 aa, and to Lactococcus lactis leucyl-tRNA synthetase LeuS or ll0816 SWALL-SYL_LACLA (SWALL-Q9CHB6) (829 aa) fasta scores- E()- 2.3e-168, 50.24% id in 830 aa; Belongs to the class-I aminoacyl-tRNA synthetase family (820 aa)
   
 
0.921
cysS
Cysteine--tRNA ligase; Similar to Leptospira interrogans cysteinyl-tRNA synthetase CysS or LA1863 SWALL-SYC_LEPIN (SWALL-Q8F525) (471 aa) fasta scores- E()- 2.3e-76, 42.25% id in 471 aa, and to Bacillus subtilis cysteinyl-tRNA synthetase CysS or SpnA SWALL-SYC_BACSU (SWALL-Q06752) (466 aa) fasta scores- E()- 1.5e-64, 38.59% id in 469 aa; Belongs to the class-I aminoacyl-tRNA synthetase family (476 aa)
 
   
  0.914
valS
Valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a "posttransfer" editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily (940 aa)
   
 
0.908
alaS
Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction- alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (875 aa)
   
 
  0.903
proS
Proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction- proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as ’pretransfer’ editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated ’posttransfer’ editing and involves deacy [...] (577 aa)
     
 
  0.895
thrS
Threonine--tRNA ligase; Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction- L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr) (635 aa)
   
 
  0.875
lysS
Lysine--tRNA ligase; Similar to Clostridium perfringens lysine-tRNA ligase LysS or CPE2465 SWALL-Q8XHL8 (EMBL-AP003194) (501 aa) fasta scores- E()- 1e-69, 42.85% id in 518 aa, and to Haemophilus influenzae lysyl-tRNA synthetase LysS or LysU or HI1211 SWALL-SYK_HAEIN (SWALL-P43825) (502 aa) fasta scores- E()- 9.4e-60, 39.88% id in 519 aa; Belongs to the class-II aminoacyl-tRNA synthetase family (526 aa)
   
 
  0.873
aspS
Aspartate--tRNA(Asp/Asn) ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps- L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily (584 aa)
   
   
  0.857
glyQ
Multifunctional fusion protein; Similar to Anabaena sp. glycyl-tRNA synthetase alpha chain GlyQ or ALL1985 SWALL-SYGA_ANASP (SWALL-Q8YVJ2) (294 aa) fasta scores- E()- 3.6e-66, 56.74% id in 289 aa, and to Tropheryma whipplei glycyl-tRNA synthetase GlyQS or TW262 SWALL-Q83I31 (EMBL-BX251410) (1024 aa) fasta scores- E()- 2.8e-77, 29.35% id in 1039 aa (1005 aa)
   
   
  0.840
Your Current Organism:
Chlamydophila abortus
NCBI taxonomy Id: 218497
Other names: C. abortus S26/3, Chlamydophila abortus, Chlamydophila abortus S26/3, Chlamydophila abortus str. S26/3
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