node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
STY0142 | STY0147 | gene:17584181 | gene:17584186 | Penicillin-binding protein 3 precursor; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.999 |
STY0142 | STY0151 | gene:17584181 | gene:17584190 | Penicillin-binding protein 3 precursor; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.986 |
STY0142 | STY0152 | gene:17584181 | gene:17584191 | Penicillin-binding protein 3 precursor; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | 0.961 |
STY0142 | STY0153 | gene:17584181 | gene:17584192 | Penicillin-binding protein 3 precursor; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.921 |
STY0142 | STY2664 | gene:17584181 | gene:17586564 | Penicillin-binding protein 3 precursor; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Cell division protein; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. | 0.649 |
STY0142 | STY3216 | gene:17584181 | gene:17587091 | Penicillin-binding protein 3 precursor; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Conserved hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. | 0.480 |
STY0142 | ftsE | gene:17584181 | gene:17588073 | Penicillin-binding protein 3 precursor; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. | 0.479 |
STY0142 | mreB | gene:17584181 | gene:17587402 | Penicillin-binding protein 3 precursor; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Rod shape-determining protein; Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature. | 0.698 |
STY0147 | STY0142 | gene:17584186 | gene:17584181 | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | Penicillin-binding protein 3 precursor; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | 0.999 |
STY0147 | STY0151 | gene:17584186 | gene:17584190 | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.994 |
STY0147 | STY0152 | gene:17584186 | gene:17584191 | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | 0.976 |
STY0147 | STY0153 | gene:17584186 | gene:17584192 | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.973 |
STY0147 | STY2664 | gene:17584186 | gene:17586564 | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | Cell division protein; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. | 0.709 |
STY0147 | STY3216 | gene:17584186 | gene:17587091 | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | Conserved hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. | 0.540 |
STY0147 | ftsE | gene:17584186 | gene:17588073 | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. | 0.610 |
STY0147 | mreB | gene:17584186 | gene:17587402 | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | Rod shape-determining protein; Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature. | 0.770 |
STY0151 | STY0142 | gene:17584190 | gene:17584181 | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | Penicillin-binding protein 3 precursor; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | 0.986 |
STY0151 | STY0147 | gene:17584190 | gene:17584186 | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.994 |
STY0151 | STY0152 | gene:17584190 | gene:17584191 | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | 0.998 |
STY0151 | STY0153 | gene:17584190 | gene:17584192 | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.969 |