node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
STY0221 | STY0223 | gene:17584257 | gene:17584258 | Ferrichrome transport protein FhuB precursor; Orthologue of E. coli fhuB (FHUB_ECOLI); Fasta hit to FHUB_ECOLI (660 aa), 90% identity in 652 aa overlap; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | Glutamate-1-semialdehyde 2,1-aminomutase; Fasta hit to GOAG_ECOLI (421 aa), 33% identity in 354 aa overlap; Fasta hit to GABT_ECOLI (426 aa), 32% identity in 421 aa overlap; Orthologue of E. coli hemL (GSA_ECOLI); Fasta hit to GSA_ECOLI (426 aa), 98% identity in 426 aa overlap. | 0.831 |
STY0221 | STY0631 | gene:17584257 | gene:17584645 | Ferrichrome transport protein FhuB precursor; Orthologue of E. coli fhuB (FHUB_ECOLI); Fasta hit to FHUB_ECOLI (660 aa), 90% identity in 652 aa overlap; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | Enterobactin synthetase component F; Orthologue of E. coli entF (ENTF_ECOLI); Fasta hit to ENTF_ECOLI (1293 aa), 79% identity in 1294 aa overlap. | 0.525 |
STY0223 | STY0221 | gene:17584258 | gene:17584257 | Glutamate-1-semialdehyde 2,1-aminomutase; Fasta hit to GOAG_ECOLI (421 aa), 33% identity in 354 aa overlap; Fasta hit to GABT_ECOLI (426 aa), 32% identity in 421 aa overlap; Orthologue of E. coli hemL (GSA_ECOLI); Fasta hit to GSA_ECOLI (426 aa), 98% identity in 426 aa overlap. | Ferrichrome transport protein FhuB precursor; Orthologue of E. coli fhuB (FHUB_ECOLI); Fasta hit to FHUB_ECOLI (660 aa), 90% identity in 652 aa overlap; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.831 |
STY0223 | STY0404 | gene:17584258 | gene:17584432 | Glutamate-1-semialdehyde 2,1-aminomutase; Fasta hit to GOAG_ECOLI (421 aa), 33% identity in 354 aa overlap; Fasta hit to GABT_ECOLI (426 aa), 32% identity in 421 aa overlap; Orthologue of E. coli hemL (GSA_ECOLI); Fasta hit to GSA_ECOLI (426 aa), 98% identity in 426 aa overlap. | Delta-aminolevulinic acid dehydratase; Orthologue of E. coli hemB (HEM2_ECOLI); Fasta hit to HEM2_ECOLI (323 aa), 94% identity in 323 aa overlap; Belongs to the ALAD family. | 0.998 |
STY0223 | STY0631 | gene:17584258 | gene:17584645 | Glutamate-1-semialdehyde 2,1-aminomutase; Fasta hit to GOAG_ECOLI (421 aa), 33% identity in 354 aa overlap; Fasta hit to GABT_ECOLI (426 aa), 32% identity in 421 aa overlap; Orthologue of E. coli hemL (GSA_ECOLI); Fasta hit to GSA_ECOLI (426 aa), 98% identity in 426 aa overlap. | Enterobactin synthetase component F; Orthologue of E. coli entF (ENTF_ECOLI); Fasta hit to ENTF_ECOLI (1293 aa), 79% identity in 1294 aa overlap. | 0.915 |
STY0223 | STY1370 | gene:17584258 | gene:17585328 | Glutamate-1-semialdehyde 2,1-aminomutase; Fasta hit to GOAG_ECOLI (421 aa), 33% identity in 354 aa overlap; Fasta hit to GABT_ECOLI (426 aa), 32% identity in 421 aa overlap; Orthologue of E. coli hemL (GSA_ECOLI); Fasta hit to GSA_ECOLI (426 aa), 98% identity in 426 aa overlap. | Psp operon transcriptional activator PspF; Orthologue of E. coli pspF (PSPF_ECOLI); Fasta hit to PSPF_ECOLI (325 aa), 87% identity in 326 aa overlap. | 0.810 |
STY0223 | STY1902 | gene:17584258 | gene:17585826 | Glutamate-1-semialdehyde 2,1-aminomutase; Fasta hit to GOAG_ECOLI (421 aa), 33% identity in 354 aa overlap; Fasta hit to GABT_ECOLI (426 aa), 32% identity in 421 aa overlap; Orthologue of E. coli hemL (GSA_ECOLI); Fasta hit to GSA_ECOLI (426 aa), 98% identity in 426 aa overlap. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.998 |
STY0223 | STY2688 | gene:17584258 | gene:17586586 | Glutamate-1-semialdehyde 2,1-aminomutase; Fasta hit to GOAG_ECOLI (421 aa), 33% identity in 354 aa overlap; Fasta hit to GABT_ECOLI (426 aa), 32% identity in 421 aa overlap; Orthologue of E. coli hemL (GSA_ECOLI); Fasta hit to GSA_ECOLI (426 aa), 98% identity in 426 aa overlap. | Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.726 |
STY0223 | STY3621 | gene:17584258 | gene:17587473 | Glutamate-1-semialdehyde 2,1-aminomutase; Fasta hit to GOAG_ECOLI (421 aa), 33% identity in 354 aa overlap; Fasta hit to GABT_ECOLI (426 aa), 32% identity in 421 aa overlap; Orthologue of E. coli hemL (GSA_ECOLI); Fasta hit to GSA_ECOLI (426 aa), 98% identity in 426 aa overlap. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.978 |
STY0223 | STY3718 | gene:17584258 | gene:17587578 | Glutamate-1-semialdehyde 2,1-aminomutase; Fasta hit to GOAG_ECOLI (421 aa), 33% identity in 354 aa overlap; Fasta hit to GABT_ECOLI (426 aa), 32% identity in 421 aa overlap; Orthologue of E. coli hemL (GSA_ECOLI); Fasta hit to GSA_ECOLI (426 aa), 98% identity in 426 aa overlap. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.699 |
STY0223 | cysG | gene:17584258 | gene:17588149 | Glutamate-1-semialdehyde 2,1-aminomutase; Fasta hit to GOAG_ECOLI (421 aa), 33% identity in 354 aa overlap; Fasta hit to GABT_ECOLI (426 aa), 32% identity in 421 aa overlap; Orthologue of E. coli hemL (GSA_ECOLI); Fasta hit to GSA_ECOLI (426 aa), 98% identity in 426 aa overlap. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.826 |
STY0223 | menF | gene:17584258 | gene:17586440 | Glutamate-1-semialdehyde 2,1-aminomutase; Fasta hit to GOAG_ECOLI (421 aa), 33% identity in 354 aa overlap; Fasta hit to GABT_ECOLI (426 aa), 32% identity in 421 aa overlap; Orthologue of E. coli hemL (GSA_ECOLI); Fasta hit to GSA_ECOLI (426 aa), 98% identity in 426 aa overlap. | Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. | 0.661 |
STY0404 | STY0223 | gene:17584432 | gene:17584258 | Delta-aminolevulinic acid dehydratase; Orthologue of E. coli hemB (HEM2_ECOLI); Fasta hit to HEM2_ECOLI (323 aa), 94% identity in 323 aa overlap; Belongs to the ALAD family. | Glutamate-1-semialdehyde 2,1-aminomutase; Fasta hit to GOAG_ECOLI (421 aa), 33% identity in 354 aa overlap; Fasta hit to GABT_ECOLI (426 aa), 32% identity in 421 aa overlap; Orthologue of E. coli hemL (GSA_ECOLI); Fasta hit to GSA_ECOLI (426 aa), 98% identity in 426 aa overlap. | 0.998 |
STY0404 | STY1902 | gene:17584432 | gene:17585826 | Delta-aminolevulinic acid dehydratase; Orthologue of E. coli hemB (HEM2_ECOLI); Fasta hit to HEM2_ECOLI (323 aa), 94% identity in 323 aa overlap; Belongs to the ALAD family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.979 |
STY0404 | STY2688 | gene:17584432 | gene:17586586 | Delta-aminolevulinic acid dehydratase; Orthologue of E. coli hemB (HEM2_ECOLI); Fasta hit to HEM2_ECOLI (323 aa), 94% identity in 323 aa overlap; Belongs to the ALAD family. | Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.602 |
STY0404 | STY3621 | gene:17584432 | gene:17587473 | Delta-aminolevulinic acid dehydratase; Orthologue of E. coli hemB (HEM2_ECOLI); Fasta hit to HEM2_ECOLI (323 aa), 94% identity in 323 aa overlap; Belongs to the ALAD family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.999 |
STY0404 | STY3718 | gene:17584432 | gene:17587578 | Delta-aminolevulinic acid dehydratase; Orthologue of E. coli hemB (HEM2_ECOLI); Fasta hit to HEM2_ECOLI (323 aa), 94% identity in 323 aa overlap; Belongs to the ALAD family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.834 |
STY0404 | cysG | gene:17584432 | gene:17588149 | Delta-aminolevulinic acid dehydratase; Orthologue of E. coli hemB (HEM2_ECOLI); Fasta hit to HEM2_ECOLI (323 aa), 94% identity in 323 aa overlap; Belongs to the ALAD family. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.919 |
STY0404 | menF | gene:17584432 | gene:17586440 | Delta-aminolevulinic acid dehydratase; Orthologue of E. coli hemB (HEM2_ECOLI); Fasta hit to HEM2_ECOLI (323 aa), 94% identity in 323 aa overlap; Belongs to the ALAD family. | Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. | 0.620 |
STY0631 | STY0221 | gene:17584645 | gene:17584257 | Enterobactin synthetase component F; Orthologue of E. coli entF (ENTF_ECOLI); Fasta hit to ENTF_ECOLI (1293 aa), 79% identity in 1294 aa overlap. | Ferrichrome transport protein FhuB precursor; Orthologue of E. coli fhuB (FHUB_ECOLI); Fasta hit to FHUB_ECOLI (660 aa), 90% identity in 652 aa overlap; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.525 |