STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY0366Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (367 aa)    
Predicted Functional Partners:
STY0367
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
 
 0.999
STY1159
Proline dehydrogenase (proline oxidase); Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family.
    
 0.982
STY3510
Similar to Escherichia coli glutamate synthase [NADPH] large chain precursor GltB SW:GLTB_ECOLI (P09831) (1517 aa) fasta scores: E(): 0, 95.4% id in 1486 aa and to Pseudomonas aeruginosa glutamate synthase large subunit GltB TR:P95456 (EMBL:U81261) (1482 aa) fasta scores: E(): 0, 60.9% id in 1476 aa.
 
   
 0.855
STY0419
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
 
 
 0.787
STY3750
Argininosuccinate lyase; Orthologue of E. coli argH (ARLY_ECOLI); Fasta hit to ARLY_ECOLI (457 aa), 95% identity in 456 aa overlap.
 
   
 0.683
STY3470
Argininosuccinate synthetase; Orthologue of E. coli argG (ASSY_ECOLI); Fasta hit to ASSY_ECOLI (446 aa), 96% identity in 446 aa overlap; Belongs to the argininosuccinate synthase family. Type 2 subfamily.
  
  
 0.620
STY3130
N-acetylglutamate synthase; Orthologue of E. coli argA (ARGA_ECOLI); Fasta hit to ARGA_ECOLI (443 aa), 94% identity in 443 aa overlap; Belongs to the acetyltransferase family. ArgA subfamily.
 
 
 
 0.583
STY0002
Aspartokinase I/homoserine dehydrogenase I; Orthologue of E. coli thrA (AK1H_ECOLI); Fasta hit to AK1H_ECOLI (820 aa), 94% identity in 820 aa overlap; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
  
 0.565
STY3768
Bifunctional aspartokinase II/homoserine dehydrogenase IIcan I write; Fasta hit to AK1H_ECOLI (820 aa), 30% identity in 823 aa overlap; Orthologue of E. coli metL (AK2H_ECOLI); Fasta hit to AK2H_ECOLI (809 aa), 94% identity in 809 aa overlap; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
  
 0.565
STY0984
Putative competence-related protein; Similar to Escherichia coli hypothetical protein YcaI SW:YCAI_ECOLI (P37443) (780 aa) fasta scores: E(): 0, 69.9% id in 754 aa, and to Pseudomonas stutzeri competence protein ComA TR:Q9XAU3 (EMBL:AJ243354) (741 aa) fasta scores: E(): 0, 31.1% id in 765 aa, and to Haemophilus influenzae recombination protein 2 rec2 or rec-2 or hi0061 SW:REC2_HAEIN (P44408) (788 aa) fasta scores: E(): 0, 30.6% id in 808 aa, and to Neisseria gonorrhoeae competence protein ComA comA SW:COMA_NEIGO (P51973) (691 aa) fasta scores: E(): 7.2e-24, 27.7% id in 703 aa; Ortholog [...]
     
 0.560
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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