STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
allBPutative allantoinase; Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring; Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family. (453 aa)    
Predicted Functional Partners:
pyrB
Similar to Salmonella typhimurium aspartate carbamoyltransferase catalytic chain PyrB SW:PYRB_SALTY (P08420) (309 aa) fasta scores: E(): 0, 98.4% id in 310 aa, and to Escherichia coli aspartate carbamoyltransferase catalytic chain PyrB SW:PYRB_ECOLI (P00479) (310 aa) fasta scores: E(): 0, 95.2% id in 310 aa; Fasta hit to OTC2_ECOLI (333 aa), 32% identity in 298 aa overlap; Fasta hit to OTC1_ECOLI (333 aa), 32% identity in 295 aa overlap.
 
 0.992
allC
Similar to Escherichia coli allantoate amidohydrolase allc or glxb7 SW:ALLC_ECOLI (P77425) (411 aa) fasta scores: E(): 0, 88.1% id in 411 aa, and to Bacillus subtilis probable allantoate amidohydrolase yurH SW:ALLC_BACSU (O32149) (412 aa) fasta scores: E(): 0, 47.8% id in 404 aa; Orthologue of E. coli YLBB_ECOLI; Fasta hit to YLBB_ECOLI (411 aa), 88% identity in 411 aa overlap.
 
 
 0.988
STY0077
Carbamoyl-phosphate synthase large chain; Orthologue of E. coli carB (CARB_ECOLI); Fasta hit to CARB_ECOLI (1072 aa), 98% identity in 1072 aa overlap.
 
 0.978
STY0076
Carbamoyl-phosphate synthase small chain; Orthologue of E. coli carA (CARA_ECOLI); Fasta hit to CARA_ECOLI (382 aa), 93% identity in 382 aa overlap; Belongs to the CarA family.
  
 0.976
STY0572
Putative permease protein; Similar to Escherichia coli hypothetical 47.5 kDa protein in gip-fdra intergenic region. putative purine permease ybby SW:YBBY_ECOLI () (435 aa) fasta scores: E(): 0, 79.0% id in 433 aa, and to Escherichia coli hypothetical 48.9 kDa protein in glts-selc intergenic region. putative purine permease yice SW:YICE_ECOLI () (463 aa) fasta scores: E(): 2.1e-11, 24.3% id in 444 aa; Orthologue of E. coli YBBY_ECOLI; Fasta hit to YBBY_ECOLI (435 aa), 79% identity in 433 aa overlap.
 
  
 0.862
STY0574
Similar to Escherichia coli hypothetical 28.7 kDa protein in gip-fdra intergenic region (glxB6 TR:O54410 (EMBL:AE000157)) SW:YLBA_ECOLI (P75713) (261 aa) fasta scores: E(): 0, 92.3% id in 261 aa; Orthologue of E. coli YLBA_ECOLI; Fasta hit to YLBA_ECOLI (261 aa), 92% identity in 261 aa overlap.
 
  
 0.779
STY1079
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
 
 0.763
STY1344
orotidine-5'-P decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
  
 0.746
STY4061
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
  
 0.746
allD
Similar to Escherichia coli ureidoglycolate dehydrogenase alld or glxb8 SW:ALLD_ECOLI (P77555) (349 aa) fasta scores: E(): 0, 86.2% id in 349 aa, and to Methanothermus fervidus malate dehydrogenase mdH SW:MDH_METFE (P16142) (339 aa) fasta scores: E(): 0, 36.4% id in 343 aa; Orthologue of E. coli YLBC_ECOLI; Fasta hit to YLBC_ECOLI (349 aa), 86% identity in 349 aa overlap; Belongs to the LDH2/MDH2 oxidoreductase family.
 
  
 0.682
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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