STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY1010Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (400 aa)    
Predicted Functional Partners:
pncA
Similar to Escherichia coli pyrazinamidase/nicotinamidase [includes: pyrazinamidase pncA or nam SW:PNCA_ECOLI (P21369; P76229; P76910) (213 aa) fasta scores: E(): 0, 80.8% id in 213 aa.
 
 
 0.994
nadR
Conserved hypothetical transcriptional regulator; Bifunctional protein. DNA binding, contains helix-turn-helix. Transporter, interacts with NcuC transporting NMN into the cell. Similar to Salmonella typhimurium transcriptional regulator NadR SW:NADR_SALTY (P24518) (409 aa) fasta scores: E(): 0, 98.8% id in 410 aa, and to Escherichia coli transcriptional regulator NadR SW:NADR_ECOLI (P27278; P76819) (410 aa) fasta scores: E(): 0, 94.6% id in 409 aa.
    
 0.991
STY0167
Nicotinate-nucleotide pyrophosphorylase; Orthologue of E. coli nadC (NADC_ECOLI); Fasta hit to NADC_ECOLI (296 aa), 86% identity in 295 aa overlap; Belongs to the NadC/ModD family.
   
 0.989
STY0696
Conserved hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.988
STY4909
Similar to Escherichia coli hypothetical 25.3 kDa protein in rimI-prfC intergenic region YjjG SW:YJJG_ECOLI (P33999; P76818) (225 aa) fasta scores: E(): 0, 90.7% id in 225 aa, and to Bacillus subtilis YfnB TR:O06480 (EMBL:D86418) (235 aa) fasta scores: E(): 6.9e-17, 28.6% id in 227 aa.
   
 
 0.944
STY3719
Conserved hypothetical protein; Orthologue of E. coli yjaD (YJAD_ECOLI); Fasta hit to YJAD_ECOLI (257 aa), 92% identity in 257 aa overlap.
    
 0.920
STY2951
Conserved hypothetical protein; Fasta hit to YDEJ_ECOLI (172 aa), 39% identity in 163 aa overlap; Orthologue of E. coli ygaD (YGAD_ECOLI); Fasta hit to YGAD_ECOLI (165 aa), 92% identity in 165 aa overlap; Belongs to the CinA family.
  
 
 0.917
STY3083
Conserved hypothetical protein; Orthologue of E. coli mazG (MAZG_ECOLI); Fasta hit to MAZG_ECOLI (263 aa), 94% identity in 262 aa overlap.
     
 0.914
deoD
Similar to Escherichia coli purine nucleoside phosphorylase deod or puP SW:DEOD_ECOLI (P09743) (238 aa) fasta scores: E(): 0, 97.1% id in 238 aa.
     
 0.912
STY2834
L-aspartate oxidase (quinolinate synthetase B); Catalyzes the oxidation of L-aspartate to iminoaspartate.
      
 0.905
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.