STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
STY1260Putative ROK-family protein; Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P. (302 aa)    
Predicted Functional Partners:
STY0723
Pts system, N-acetylglucosamine-specific IIABC component; Orthologue of E. coli nagE (PTAA_ECOLI); Fasta hit to PTAA_ECOLI (648 aa), 93% identity in 648 aa overlap.
  
 0.982
STY1166
Conserved hypothetical protein; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P).
 
 
 0.928
STY2817
Putative phophosugar binding protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
    
 0.928
STY0721
N-acetylglucosamine-6-phosphate deacetylase; Orthologue of E. coli nagA (NAGA_ECOLI); Fasta hit to NAGA_ECOLI (382 aa), 92% identity in 380 aa overlap.
 
 
 0.922
STY1249
Putative glycosyl hydrolase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
    
 0.902
STY1259
ABC transporter integral membrane subunit; Orthologue of E. coli YCFW_ECOLI; Fasta hit to YCFW_ECOLI (414 aa), 93% identity in 414 aa overlap.
      0.856
STY1576
Putative regulatory protein; Fasta hit to NAGC_ECOLI (406 aa), 40% identity in 385 aa overlap; Orthologue of E. coli mlc (MLC_ECOLI); Fasta hit to MLC_ECOLI (406 aa), 91% identity in 386 aa overlap.
 
     0.778
STY1242
PTS system, glucose-specific IIBC component; Fasta hit to PTOA_ECOLI (530 aa), 37% identity in 513 aa overlap; Orthologue of E. coli ptsG (PTGB_ECOLI); Fasta hit to PTGB_ECOLI (477 aa), 97% identity in 476 aa overlap.
  
 
 0.743
STY2816
Putative PTS system IIBC component; Similar to Bacillus subtilis negative regulatory protein of SacY sacX or sacS SW:SACX_BACSU (P15400) (459 aa) fasta scores: E(): 0, 33.1% id in 472 aa and putative PTS components e.g. Bacillus halodurans putative PTS system, sucrose phosphotransferase enzyme II BC component BH3574 TR:Q9K700 (EMBL:AP001519) (453 aa) fasta scores: E(): 0, 47.4% id in 454 aa; Orthologue of E. coli P77272; Fasta hit to P77272 (474 aa), 39% identity in 470 aa overlap.
  
 
 0.743
treB
Similar to Escherichia coli pts system, trehalose-specific IIBC component treB SW:PTTB_ECOLI (P36672) (473 aa) fasta scores: E(): 0, 89.0% id in 472 aa and to Bacillus subtilis probable pts system, trehalose-specific IIBC component TreP treP or treB SW:PTTB_BACSU (P39794) (470 aa) fasta scores: E(): 0, 41.0% id in 463 aa.
  
 
 0.743
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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