STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY1312Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. (486 aa)    
Predicted Functional Partners:
STY1341
Orthologue of E. coli pgpB (PGPB_ECOLI); Fasta hit to PGPB_ECOLI (254 aa), 83% identity in 254 aa overlap.
    
 0.946
STY1185
Conserved hypothetical protein; Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) from phosphatidylglycerol (PG) and phosphatidylethanolamine (PE); Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsC sub-subfamily.
  
  
0.934
ybhO
Putative phospholipase; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
  
  
0.930
STY0459
Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).
     
 0.910
STY2815
Putative membrane protein; Orthologue of E. coli yfhB (YFHB_ECOLI); Fasta hit to YFHB_ECOLI (211 aa), 91% identity in 211 aa overlap. Contains an hydrophobic, possible membrane-spanning region.
     
 0.910
STY1313
Similar to Neisseria meningitidis conserved hypothetical protein nma2144 TR:CAB85356 (EMBL:AL162758) (96 aa) fasta scores: E(): 8.8e-17, 50.5% id in 97 aa; Orthologue of E. coli yciI (YCII_ECOLI); Fasta hit to YCII_ECOLI (98 aa), 91% identity in 98 aa overlap.
      0.689
STY1311
Similar to Haemophilus influenzae hypothetical protein Hi1450 hi1450 SW:YCIU_HAEIN (P44199) (107 aa) fasta scores: E(): 3.1e-19, 46.1% id in 102 aa; Orthologue of E. coli YCIU_ECOLI; Fasta hit to YCIU_ECOLI (109 aa), 94% identity in 109 aa overlap; Belongs to the UPF0263 family.
       0.679
kefB
Glutathione-regulated potassium-efflux system protein (K(+)/H(+)antiporter); Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.
      
 0.624
mscL
Large-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
      
 0.538
STY1504
Putative hydrolase; Similar to Rhizobium sp maltooligosyl trehalose synthase treY TR:Q53237 (EMBL:D78001) (772 aa) fasta scores: E(): 4.7e-26, 37.0% id in 832 aa.
     
 0.482
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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