STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurrence
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[Homology]
Score
STY1331Putative pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA; Belongs to the pseudouridine synthase RsuA family. (291 aa)    
Predicted Functional Partners:
STY1227
Ribosomal large subunit pseudouridine synthase C (EC 4.2.1.70); Responsible for synthesis of pseudouridine from uracil at positions 955, 2504 and 2580 in 23S ribosomal RNA; Belongs to the pseudouridine synthase RluA family.
 
 
 
 0.850
STY2764
Putative GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
 
  
 0.835
STY0980
Cytidylate kinase; Orthologue of E. coli cmk (KCY_ECOLI); Fasta hit to KCY_ECOLI (227 aa), 98% identity in 227 aa overlap.
  
 0.747
rluA
Ribosomal large subunit pseudouridine synthase A; Dual specificity enzyme that catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs.
   
 
 0.658
STY1330
Conserved hypothetical protein; Orthologue of E. coli yciO (YCIO_ECOLI); Fasta hit to YCIO_ECOLI (206 aa), 93% identity in 206 aa overlap; Belongs to the SUA5 family.
  
  
 0.577
STY1329
Conserved hypothetical protein; Orthologue of E. coli TRPH_ECOLI; Fasta hit to TRPH_ECOLI (293 aa), 91% identity in 286 aa overlap.
       0.564
STY1812
Exodeoxyribonuclease III; Major apurinic-apyrimidinic endonuclease of E.coli. It removes the damaged DNA at cytosines and guanines by cleaving on the 3'-side of the AP site by a beta-elimination reaction. It exhibits 3'- 5'-exonuclease, 3'-phosphomonoesterase, 3'-repair diesterase and ribonuclease H activities (By similarity).
  
    0.535
yqcB
Putative RNA pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil-65 in transfer RNAs; Belongs to the pseudouridine synthase RluA family.
   
 
 0.513
STY3905
Glucose inhibited division protein; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
  
     0.508
STY2851
ftsH suppressor protein SfhB; Responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; Belongs to the pseudouridine synthase RluA family.
 
 
 
 0.504
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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