STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY1682Copper-zinc superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (173 aa)    
Predicted Functional Partners:
STY0544
Copper-transporting ATPase; [Copper-exporting P-type ATPase]: Involved in Cu(+) export (By similarity).
   
 0.989
STY3816
Manganese superoxide dismutase; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the iron/manganese superoxide dismutase family.
   
 
 0.952
STY1691
Superoxide dismutase; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
   
 
 0.951
STY1793
Catalase HPII; Serves to protect cells from the toxic effects of hydrogen peroxide.
 
 0.935
STY3760
Catalase (hydroperoxidase I); Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.
     
 0.887
STY0653
Alkyl hydroperoxide reductase c22 protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
   
 
 0.825
STY3749
Hydrogen peroxide-inducible regulon activator; Fasta hit to YNFL_ECOLI (297 aa), 32% identity in 248 aa overlap; Fasta hit to CYNR_ECOLI (299 aa), 31% identity in 273 aa overlap; Orthologue of E. coli oxyR (OXYR_ECOLI); Fasta hit to OXYR_ECOLI (305 aa), 96% identity in 305 aa overlap; Belongs to the LysR transcriptional regulatory family.
      
 0.628
STY3452
Conserved hypothetical protein; Similar to several including: Bacillus subtilis general stress protein 18 yfkM SW:GS18_BACSU (P80876) (171 aa) fasta scores: E(): 0, 64.9% id in 168 aa, and to Pyrococcus furiosus protease I pfpI SW:PFPI_PYRFU (Q51732) (166 aa) fasta scores: E(): 6.5e-24, 47.9% id in 167 aa; Orthologue of E. coli yhbO (YHBO_ECOLI); Fasta hit to YHBO_ECOLI (172 aa), 95% identity in 172 aa overlap.
  
 
 0.601
STY1683
Putative oxidoreductase; Fasta hit to P76234 (284 aa), 32% identity in 266 aa overlap; Orthologue of E. coli YDHF_ECOLI; Fasta hit to YDHF_ECOLI (298 aa), 89% identity in 298 aa overlap.
  
    0.566
STY0931
Pyruvate dehydrogenase; Fasta hit to ILVI_ECOLI (574 aa), 30% identity in 560 aa overlap; Orthologue of E. coli poxB (POXB_ECOLI); Fasta hit to POXB_ECOLI (572 aa), 94% identity in 572 aa overlap; Belongs to the TPP enzyme family.
   
  
 0.541
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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