STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spiASimilar to Salmonella typhimurium outer membrane secretory protein SpiA TR:P74864 (EMBL:U51927) (497 aa) fasta scores: E(): 0, 99.4% id in 497 aa, and to Yersinia pestis kim5 or yscc or ypcd1.52 TR:Q56974 (EMBL:M83225) (607 aa) fasta scores: E(): 7.8e-32, 32.9% id in 507 aa. (497 aa)    
Predicted Functional Partners:
ssaJ
Putative pathogenicity island lipoprotein; Similar to Salmonella typhimurium secretion system apparatus lipoprotein SsaJ SW:SSAJ_SALTY () (249 aa) fasta scores: E(): 0, 98.8% id in 249 aa.
 
 
 0.998
ssaD
Putative pathogenicity island protein; Similar to Salmonella typhimurium SsaD or SpiB TR:O84942 (EMBL:AJ224892) (231 aa) fasta scores: E(): 0, 98.7% id in 231 aa.
  
  
 0.996
ssaT
Putative type III secretion protein; Similar to Salmonella typhimurium secretion system apparatus protein SsaT SW:SSAT_SALTY (P96068) (259 aa) fasta scores: E(): 0, 98.5% id in 259 aa, and to Yersinia pestis type III secretion protein YscT TR:AAC69785 (EMBL:AF074612) (261 aa) fasta scores: E(): 6.2e-22, 33.3% id in 234 aa.
 
 
 0.978
sscA
Putative Type III secretion system chaperone protein; Similar to Salmonella typhimurium putative secretion chaperone SscA TR:O84946 (EMBL:AF020808) (157 aa) fasta scores: E(): 0, 98.1% id in 157 aa, and to Escherichia coli CesD TR:O52134 (EMBL:AF022236) (151 aa) fasta scores: E(): 5.6e-09, 29.5% id in 139 aa.
 
  
 0.968
ssaV
Putative type III secretion protein; Similar to Salmonella typhimurium secretion system apparatus protein SsaV SW:SSAV_SALTY (P74856) (681 aa) fasta scores: E(): 0, 99.3% id in 681 aa, and to Escherichia coli SepA protein sepA TR:Q47629 (EMBL:Z49933) (643 aa) fasta scores: E(): 0, 49.8% id in 608 aa; Paralogue of E. coli flhA (FLHA_ECOLI); Fasta hit to FLHA_ECOLI (692 aa), 33% identity in 692 aa overlap.
 
 
 0.963
ssrA
Putative two-component sensor kinase; Similar to Salmonella typhimurium SpiR TR:P74862 (EMBL:U51927) (823 aa) fasta scores: E(): 0, 98.1% id in 823 aa, and to Escherichia coli sensor protein TorS SW:TORS_ECOLI (P39453; P75887) (904 aa) fasta scores: E(): 1.3e-26, 27.8% id in 598 aa.
 
  
 0.959
sseB
Putative pathogenicity island effector effector protein; Similar to Salmonella typhimurium putative secreted protein SseB TR:O84945 (EMBL:AF020808) (196 aa) fasta scores: E(): 0, 100.0% id in 196 aa.
  
  
 0.957
yscR
Putative type III secretion protein; Similar to Salmonella typhimurium virulence protein YscR SW:YSCR_SALTY (P74890) (215 aa) fasta scores: E(): 0, 99.5% id in 215 aa, and to Yersinia pestis type III secretion protein YscR TR:AAC69787 (EMBL:AF074612) (217 aa) fasta scores: E(): 0, 54.0% id in 215 aa; Paralogue of E. coli fliP (FLIP_ECOLI); Fasta hit to FLIP_ECOLI (245 aa), 40% identity in 209 aa overlap.
 
 
 0.944
ssaL
Similar to Salmonella typhimurium secretion system apparatus protein SsaL SW:SSAL_SALTY () (338 aa) fasta scores: E(): 0, 97.6% id in 330 aa. Note discrepency in predicted translational start site.
  
  
 0.939
sseD
Putative pathogenicity island effector protein; Similar to Salmonella typhimurium SseD TR:Q9R803 (EMBL:AJ224892) (195 aa) fasta scores: E(): 0, 98.5% id in 195 aa.
  
  
 0.936
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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