STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY1815NADP-specific glutamate dehydrogenase; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. (447 aa)    
Predicted Functional Partners:
STY3510
Similar to Escherichia coli glutamate synthase [NADPH] large chain precursor GltB SW:GLTB_ECOLI (P09831) (1517 aa) fasta scores: E(): 0, 95.4% id in 1486 aa and to Pseudomonas aeruginosa glutamate synthase large subunit GltB TR:P95456 (EMBL:U81261) (1482 aa) fasta scores: E(): 0, 60.9% id in 1476 aa.
  
 0.998
STY3874
Glutamine synthetase; Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family.
  
 
 0.966
STY1000
Aspartate aminotransferase; Fasta hit to TYRB_ECOLI (397 aa), 43% identity in 397 aa overlap; Orthologue of E. coli aspC (AAT_ECOLI); Fasta hit to AAT_ECOLI (396 aa), 96% identity in 396 aa overlap; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
   
 0.956
STY1159
Proline dehydrogenase (proline oxidase); Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family.
  
 
 0.953
STY3511
Glutamate synthase (NADPH) small chain; Fasta hit to P76440 (412 aa), 33% identity in 443 aa overlap; Orthologue of E. coli gltD (GLTD_ECOLI); Fasta hit to GLTD_ECOLI (471 aa), 95% identity in 471 aa overlap.
  
 0.944
STY0353
Possible hydrolase; Similar to many hypothetical proteins e.g. Escherichia coli hypothetical protein in agr operon TR:Q9R2E1 (EMBL:D83536) (259 aa) fasta scores: E(): 0, 82.0% id in 255 aa, and to Bacillus subtilis YkrU protein ykrU TR:O31664 (EMBL:Z99111) (259 aa) fasta scores: E(): 4.3e-25, 32.7% id in 251 aa; Orthologue of E. coli YAFV_ECOLI; Fasta hit to YAFV_ECOLI (256 aa), 82% identity in 253 aa overlap.
   
 
 0.921
STY3130
N-acetylglutamate synthase; Orthologue of E. coli argA (ARGA_ECOLI); Fasta hit to ARGA_ECOLI (443 aa), 94% identity in 443 aa overlap; Belongs to the acetyltransferase family. ArgA subfamily.
  
 
 0.918
nirB
Similar to Escherichia coli nitrite reductase [NAD nirB SW:NIRB_ECOLI (P08201) (847 aa) fasta scores: E(): 0, 95.0% id in 847 aa; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
   
 
 0.912
STY0933
Prismane protein homolog (hybrid-cluster protein); Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
     
 0.910
STY2561
Putative aminotransferase; Similar to Methylobacillus flagellatum aspartate aminotransferase aat TR:Q9RAN0 (EMBL:L78665) (429 aa) fasta scores: E(): 0, 62.1% id in 404 aa and to many putative aminotransferases; Orthologue of E. coli YFBQ_ECOLI; Fasta hit to YFBQ_ECOLI (405 aa), 97% identity in 404 aa overlap.
  
 
 0.907
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.