STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY2161Putative deaminase; Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine; Belongs to the ACC deaminase/D-cysteine desulfhydrase family. (328 aa)    
Predicted Functional Partners:
STY2779
Putative thiosulfate sulfurtransferase; Similar to many eukaryotic proteins e.g. Homo sapiens 3-mercaptopyruvate sulfurtransferase mpsT or tst2 SW:THTM_HUMAN (P25325) (296 aa) fasta scores: E(): 0, 41.1% id in 280 aa; Orthologue of E. coli sseA (THTR_ECOLI); Fasta hit to THTR_ECOLI (280 aa), 81% identity in 278 aa overlap.
 
  
  0.912
STY1507
Putative aminotransferase; Orthologue of E. coli malY (MALY_ECOLI); Fasta hit to MALY_ECOLI (390 aa), 34% identity in 384 aa overlap.
    
  0.903
STY3333
Beta-cystathionase; Fasta hit to METB_ECOLI (386 aa), 32% identity in 398 aa overlap; Orthologue of E. coli metC (METC_ECOLI); Fasta hit to METC_ECOLI (395 aa), 87% identity in 395 aa overlap.
     
 0.901
STY2160
Putative ABC transporter membrane protein; Similar to Escherichia coli hypothetical amino-acid ABC transporter permease protein YecS yecS SW:YECS_ECOLI (P76315) (222 aa) fasta scores: E(): 0, 93.2% id in 222 aa, and to Deinococcus radiodurans amino acid ABC transporter, permease protein dr0565 TR:Q9RWV0 (EMBL:AE001914) (226 aa) fasta scores: E(): 0, 50.5% id in 216 aa; Fasta hit to GLTK_ECOLI (224 aa), 38% identity in 212 aa overlap; Fasta hit to ARTQ_ECOLI (238 aa), 34% identity in 236 aa overlap; Fasta hit to ARTM_ECOLI (222 aa), 37% identity in 224 aa overlap; Fasta hit to GLNP_ECOL [...]
  
  
 0.795
STY2159
Similar to many ABC-transporter ATP-binding proteins, mostly of amino-acid (or related) transport systeams e.g. Agrobacterium tumefaciens octopine permease ATP-binding protein P SW:OCCP_AGRT6 (P35117) (262 aa) fasta scores: E(): 0, 52.6% id in 249 aa; Fasta hit to ARTP_ECOLI (242 aa), 48% identity in 238 aa overlap; Fasta hit to FEPC_ECOLI (271 aa), 30% identity in 222 aa overlap; Fasta hit to YCFV_ECOLI (233 aa), 36% identity in 229 aa overlap; Fasta hit to SSUB_ECOLI (255 aa), 37% identity in 217 aa overlap; Fasta hit to YBBA_ECOLI (228 aa), 38% identity in 229 aa overlap; Fasta hit [...]
  
  
 0.783
STY2814
Conserved hypothetical protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
      
 0.738
fliY
Similar to Escherichia coli cystine-binding periplasmic protein precursor fliY SW:FLIY_ECOLI (P39174) (266 aa) fasta scores: E(): 0, 92.5% id in 266 aa and Salmonella typhimurium FliY fliY TR:Q9ZNM2 (EMBL:AB010947) (266 aa) fasta scores: E(): 0, 98.9% id in 266 aa. Contains a probable N-terminal signal sequence; Orthologue of E. coli fliY (FLIY_ECOLI); Fasta hit to FLIY_ECOLI (266 aa), 93% identity in 266 aa overlap; Belongs to the bacterial solute-binding protein 3 family.
 
  
 0.679
STY0979
Putative lipoprotein; Fasta hit to YGGG_ECOLI (252 aa), 56% identity in 251 aa overlap; Orthologue of E. coli YCAL_ECOLI; Fasta hit to YCAL_ECOLI (254 aa), 70% identity in 254 aa overlap. Contains probable N-terminal signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
      
 0.648
STY3237
Conserved hypothetical protein; Fasta hit to YCAL_ECOLI (254 aa), 59% identity in 252 aa overlap; Orthologue of E. coli yggG (YGGG_ECOLI); Fasta hit to YGGG_ECOLI (252 aa), 91% identity in 252 aa overlap.
      
 0.648
STY1198
Putative sarcosine oxidase; Catalyzes the oxidative demethylation of N-methyl-L- tryptophan; Belongs to the MSOX/MTOX family. MTOX subfamily.
  
   
 0.555
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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