STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fliCFlagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. (506 aa)    
Predicted Functional Partners:
fliS
Flagellar protein FliS; Similar to Salmonella typhimurium flagellar protein FliS fliS SW:FLIS_SALTY (P26609) (135 aa) fasta scores: E(): 0, 99.3% id in 135 aa; Orthologue of E. coli fliS (FLIS_ECOLI); Fasta hit to FLIS_ECOLI (136 aa), 62% identity in 129 aa overlap.
 
 
 0.998
fliD
Flagellar hook associated protein 2; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
 
 
 0.996
STY1222
Flagellar hook-associated protein 1; Orthologue of E. coli flgK (FLGK_ECOLI); Fasta hit to FLGK_ECOLI (546 aa), 80% identity in 554 aa overlap.
 
  
 0.982
STY1223
Flagellar hook-associated protein 3; Orthologue of E. coli flgL (FLGL_ECOLI); Fasta hit to FLGL_ECOLI (317 aa), 82% identity in 317 aa overlap.
 
  
 0.974
STY1216
Flagellar hook protein FlgE; Orthologue of E. coli flgE (FLGE_ECOLI); Fasta hit to FLGE_ECOLI (401 aa), 88% identity in 403 aa overlap.
 
  
 0.967
STY1213
Putative flagellar basal-body rod protein FlgB (proximal rod protein); Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
 
 
 0.962
STY1221
Flagellar protein FlgJ; Orthologue of E. coli flgJ (FLGJ_ECOLI); Fasta hit to FLGJ_ECOLI (313 aa), 83% identity in 316 aa overlap.
 
  
 0.962
fliA
RNA polymerase sigma transcription factor for flagellar operon; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.
 
  
 0.961
STY1214
Putative flagellar basal-body rod protein FlgC (proximal rod protein); Orthologue of E. coli flgC (FLGC_ECOLI); Fasta hit to FLGC_ECOLI (134 aa), 93% identity in 134 aa overlap; Belongs to the flagella basal body rod proteins family.
 
  
 0.957
STY1218
Flagellar basal-body rod protein FlgG (distal rod protein); Fasta hit to FLGF_ECOLI (251 aa), 32% identity in 261 aa overlap; Orthologue of E. coli flgG (FLGG_ECOLI); Fasta hit to FLGG_ECOLI (260 aa), 99% identity in 260 aa overlap; Belongs to the flagella basal body rod proteins family.
 
 
 0.957
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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