STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY2260Identical to Salmonella typhimurium propanediol utilization protein pduU SW:PDUU_SALTY (Q9XDM7) (116 aa) fasta scores: E(): 0, 100.0% id in 116 aa and Salmonella typhimurium ethanolamine utilization protein eutS SW:EUTS_SALTY (P76557) (111 aa) fasta scores: E(): 3.4e-22, 57.8% id in 109 aa. The Salmonella enterica homologue has been implicated in polyhedral body formation which may protect the cell from toxic metabolites, or protect the dehydratase from oxygen. (116 aa)    
Predicted Functional Partners:
pduT
Putative propanediol utilization protein PduT; Similar to Salmonella enterica serovar Typhimurium protein PduT pduT TR:Q9XDM8 (EMBL:AF026270) (184 aa) fasta scores: E(): 0, 98.9% id in 184 aa and to part of Salmonella typhimurium ethanolamine utilization protein EutM precursor eutM or cchA SW:EUTM_SALTY (P41791) (96 aa) fasta scores: E(): 0.00067, 40.0% id in 80 aa. The Salmonella enterica homologue has been implicated in polyhedral body formation which may protect the cell from toxic metabolites, or protect the dehydratase from oxygen.
 
  
 0.996
pduV
Similar to Salmonella typhimurium propanediol utilization protein pduV SW:PDUV_SALTY (Q9XDM6) (150 aa) fasta scores: E(): 0, 97.3% id in 150 aa and Salmonella typhimurium ethanolamine utilization protein eutP SW:EUTP_SALTY (Q9ZFV6) (159 aa) fasta scores: E(): 2.7e-08, 32.2% id in 143 aa; Belongs to the EutP/PduV family.
 
  
 0.992
pduA
Similar to Salmonella typhimurium propanediol utilization protein PduA pduA SW:PDUA_SALTY (P37448) (97 aa) fasta scores: E(): 5.7e-31, 100.0% id in 90 aa and identical to Salmonella enterica serovar Typhimurium PduA pduA TR:AAB84107 (EMBL:AF026270) (94 aa) fasta scores: E(): 1.1e-32, 100.0% id in 94 aa. S. typhi pduA is probably not essential for propanediol catabolism (by similarity), but may be involved (cf. homologue in the eut operon). The Salmonella enterica homologue has been implicated in polyhedral body formation which may protect the cell from toxic metabolites, or protect the [...]
 
  
 0.976
pduK
Putative propanediol utilization protein PduK; Similar to Salmonella enterica serovar Typhimurium protein PduK pduK TR:Q9XDN6 (EMBL:AF026270) (160 aa) fasta scores: E(): 0, 98.1% id in 160 aa. The Salmonella enterica homologue has been implicated in polyhedral body formation which may protect the cell from toxic metabolites, or protect the dehydratase from oxygen.
 
  
 0.975
pduJ
Putative propanediol utilization protein PduJ; Similar to Salmonella enterica serovar Typhimurium protein PduJ pduJ TR:Q9XDN7 (EMBL:AF026270) (91 aa) fasta scores: E(): 4.2e-31, 100.0% id in 91 aa, Salmonella typhimurium propanediol utilization protein PduA pduA SW:PDUA_SALTY (P37448) (97 aa) fasta scores: E(): 6.7e-24, 84.9% id in 86 aa and Salmonella typhimurium ethanolamine utilization protein EutM precursor eutM or cchA SW:EUTM_SALTY (P41791) (96 aa) fasta scores: E(): 4.1e-18, 64.4% id in 87 aa. The Salmonella enterica homologue has been implicated in polyhedral body formation whi [...]
 
  
 0.968
pduP
Putative CoA-dependent proprionaldehyde dehydrogenase; Similar to Salmonella enterica serovar Typhimurium protein PduP pduP TR:Q9XDN1 (EMBL:AF026270) (464 aa) fasta scores: E(): 0, 99.1% id in 464 aa and Salmonella typhimurium ethanolamine utilization protein EutE eutE SW:EUTE_SALTY (P41793) (467 aa) fasta scores: E(): 0, 45.7% id in 473 aa; Paralogue of E. coli eutE (EUTE_ECOLI); Fasta hit to EUTE_ECOLI (467 aa), 45% identity in 470 aa overlap.
 
  
 0.957
eutL
Ethanolamine utilization protein EutL; May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place; Belongs to the EutL/PduB family.
 
   
 0.953
pduB
Similar to Salmonella typhimurium propanediol utilization protein PduB pduB SW:PDUB_SALTY (P37449) (233 aa) fasta scores: E(): 0, 99.1% id in 233 aa. S. typhi pduB is probably not essential for propanediol catabolism (by similarity), but may be involved (cf. homologue in the eut operon). The Salmonella enterica homologue has been implicated in polyhedral body formation which may protect the cell from toxic metabolites, or protect the dehydratase from oxygen.
 
   
 0.952
pduO
Conserved hypothetical protein; Similar to Salmonella enterica serovar Typhimurium protein PduO pduO TR:Q9XDN2 (EMBL:AF026270) (337 aa) fasta scores: E(): 0, 92.6% id in 337 aa. N-terminal half is similar to many e.g. Clostridium pasteurianum hypothetical protein TR:O30452 (EMBL:AF006034) (173 aa) fasta scores: E(): 2.3e-21, 43.7% id in 167 aa and Citrobacter freundii hypothetical protein SW:YDHW_CITFR (P45515) (176 aa) fasta scores: E(): 3.2e-25, 47.9% id in 167 aa. C-terminal half is similar to many e.g. Clostridium pasteurianum hypothetical protein TR:O30453 (EMBL:AF006034) (143 aa) [...]
 
   
 0.951
pduS
Putative ferredoxin; Similar to Salmonella enterica serovar Typhimurium protein PduS pduS TR:Q9XDM9 (EMBL:AF026270) (451 aa) fasta scores: E(): 0, 97.7% id in 442 aa and Clostridium sticklandii electron transfer protein from the D-proline reductase cluster prdC TR:Q9L4Q5 (EMBL:AJ130879) (402 aa) fasta scores: E(): 1.5e-24, 32.3% id in 337 aa. The N-terminus is truncated by 9 amino acids with respect to the Salmonella enterica homologue (by a stop codon). The putative start codon indicated here is at codon 10 of the Salmonella enterica homologue.
 
  
 0.912
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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