node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
STY0455 | STY2376 | gene:17584477 | gene:17586281 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.595 |
STY0455 | STY3721 | gene:17584477 | gene:17587581 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.530 |
STY0455 | STY3726 | gene:17584477 | gene:17587586 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Thiamine biosynthesis protein; Orthologue of E. coli thiH (THIH_ECOLI); Fasta hit to THIH_ECOLI (377 aa), 90% identity in 375 aa overlap. | 0.425 |
STY0455 | STY4416 | gene:17584477 | gene:17588248 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Similar to Escherichia coli lysine-sensitive aspartokinase III LysC SW:AK3_ECOLI (P08660) (449 aa) fasta scores: E(): 0, 93.3% id in 449 aa; Belongs to the aspartokinase family. | 0.421 |
STY0455 | thiD | gene:17584477 | gene:17586280 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Phosphomethylpyrimidine kinase; Similar to Salmonella typhimurium LT2 phosphomethylpyrimidine kinase SW:THID_SALTY (P55882) (266 aa) fasta scores: E(): 0, 99.2% id in 266 aa; Orthologue of E. coli THID_ECOLI; Fasta hit to THID_ECOLI (266 aa), 91% identity in 266 aa overlap. | 0.611 |
STY0455 | thiE | gene:17584477 | gene:17587582 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.527 |
STY2374 | STY2376 | gene:17586279 | gene:17586281 | Putative gntR-family transcriptional regulator; Orthologue of E. coli YEGW_ECOLI; Fasta hit to YEGW_ECOLI (248 aa), 92% identity in 248 aa overlap. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.676 |
STY2374 | thiD | gene:17586279 | gene:17586280 | Putative gntR-family transcriptional regulator; Orthologue of E. coli YEGW_ECOLI; Fasta hit to YEGW_ECOLI (248 aa), 92% identity in 248 aa overlap. | Phosphomethylpyrimidine kinase; Similar to Salmonella typhimurium LT2 phosphomethylpyrimidine kinase SW:THID_SALTY (P55882) (266 aa) fasta scores: E(): 0, 99.2% id in 266 aa; Orthologue of E. coli THID_ECOLI; Fasta hit to THID_ECOLI (266 aa), 91% identity in 266 aa overlap. | 0.722 |
STY2376 | STY0455 | gene:17586281 | gene:17584477 | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.595 |
STY2376 | STY2374 | gene:17586281 | gene:17586279 | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | Putative gntR-family transcriptional regulator; Orthologue of E. coli YEGW_ECOLI; Fasta hit to YEGW_ECOLI (248 aa), 92% identity in 248 aa overlap. | 0.676 |
STY2376 | STY3721 | gene:17586281 | gene:17587581 | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | Thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.770 |
STY2376 | STY3723 | gene:17586281 | gene:17587583 | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | Thiamine biosynthesis protein; Fasta hit to MOEB_ECOLI (249 aa), 45% identity in 245 aa overlap; Orthologue of E. coli thiF (THIF_ECOLI); Fasta hit to THIF_ECOLI (251 aa), 87% identity in 251 aa overlap. | 0.756 |
STY2376 | STY3725 | gene:17586281 | gene:17587585 | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | Thiamine biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.651 |
STY2376 | STY3726 | gene:17586281 | gene:17587586 | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | Thiamine biosynthesis protein; Orthologue of E. coli thiH (THIH_ECOLI); Fasta hit to THIH_ECOLI (377 aa), 90% identity in 375 aa overlap. | 0.756 |
STY2376 | STY4416 | gene:17586281 | gene:17588248 | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | Similar to Escherichia coli lysine-sensitive aspartokinase III LysC SW:AK3_ECOLI (P08660) (449 aa) fasta scores: E(): 0, 93.3% id in 449 aa; Belongs to the aspartokinase family. | 0.614 |
STY2376 | fbaB | gene:17586281 | gene:17586275 | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | Similar to Escherichia coli fructose-bisphosphate aldolase class I FbaB or DhnA SW:ALF1_ECOLI (P71295) (349 aa) fasta scores: E(): 0, 96.0% id in 349 aa; Orthologue of E. coli ALF1_ECOLI; Fasta hit to ALF1_ECOLI (349 aa), 96% identity in 349 aa overlap. | 0.584 |
STY2376 | thiD | gene:17586281 | gene:17586280 | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | Phosphomethylpyrimidine kinase; Similar to Salmonella typhimurium LT2 phosphomethylpyrimidine kinase SW:THID_SALTY (P55882) (266 aa) fasta scores: E(): 0, 99.2% id in 266 aa; Orthologue of E. coli THID_ECOLI; Fasta hit to THID_ECOLI (266 aa), 91% identity in 266 aa overlap. | 0.999 |
STY2376 | thiE | gene:17586281 | gene:17587582 | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.997 |
STY3721 | STY0455 | gene:17587581 | gene:17584477 | Thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.530 |
STY3721 | STY2376 | gene:17587581 | gene:17586281 | Thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.770 |