node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
STY0132 | STY1278 | gene:17584172 | gene:17585242 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | Isocitrate dehydrogenase; Orthologue of E. coli icdA (IDH_ECOLI); Fasta hit to IDH_ECOLI (416 aa), 97% identity in 416 aa overlap. | 0.453 |
STY0132 | STY2561 | gene:17584172 | gene:17586460 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | Putative aminotransferase; Similar to Methylobacillus flagellatum aspartate aminotransferase aat TR:Q9RAN0 (EMBL:L78665) (429 aa) fasta scores: E(): 0, 62.1% id in 404 aa and to many putative aminotransferases; Orthologue of E. coli YFBQ_ECOLI; Fasta hit to YFBQ_ECOLI (405 aa), 97% identity in 404 aa overlap. | 0.912 |
STY0132 | STY3653 | gene:17584172 | gene:17587508 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | Dihydroxyacid dehydratase; Similar to Escherichia coli dihydroxy-acid dehydratase SW:ILVD_ECOLI () (605 aa) fasta scores: E(): 0, 93.9% id in 602 aa and to Haemophilus influenzae dihydroxy-acid dehydratase IlvD SW:ILVD_HAEIN (P44851) (612 aa) fasta scores: E(): 0, 76.9% id in 614 aa. Note that the N-terminus of this CDS is more similar to the H. influenzae IlvD; Fasta hit to YAGF_ECOLI (655 aa), 30% identity in 543 aa overlap; Orthologue of E. coli ilvD (ILVD_ECOLI); Fasta hit to ILVD_ECOLI (605 aa), 94% identity in 602 aa overlap; Belongs to the IlvD/Edd family. | 0.992 |
STY0132 | STY3654 | gene:17584172 | gene:17587509 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | Branched-chain amino-acid aminotransferase; Acts on leucine, isoleucine and valine. | 0.996 |
STY0132 | STY4133 | gene:17584172 | gene:17587975 | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | Valine--pyruvate aminotransferase; Orthologue of E. coli avtA (AVTA_ECOLI); Fasta hit to AVTA_ECOLI (417 aa), 92% identity in 415 aa overlap. | 0.913 |
STY0776 | STY1000 | gene:17584782 | gene:17584989 | Succinate dehydrogenase hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). | Aspartate aminotransferase; Fasta hit to TYRB_ECOLI (397 aa), 43% identity in 397 aa overlap; Orthologue of E. coli aspC (AAT_ECOLI); Fasta hit to AAT_ECOLI (396 aa), 96% identity in 396 aa overlap; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | 0.804 |
STY0776 | STY1653 | gene:17584782 | gene:17585588 | Succinate dehydrogenase hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.917 |
STY0776 | STY2561 | gene:17584782 | gene:17586460 | Succinate dehydrogenase hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). | Putative aminotransferase; Similar to Methylobacillus flagellatum aspartate aminotransferase aat TR:Q9RAN0 (EMBL:L78665) (429 aa) fasta scores: E(): 0, 62.1% id in 404 aa and to many putative aminotransferases; Orthologue of E. coli YFBQ_ECOLI; Fasta hit to YFBQ_ECOLI (405 aa), 97% identity in 404 aa overlap. | 0.833 |
STY1000 | STY0776 | gene:17584989 | gene:17584782 | Aspartate aminotransferase; Fasta hit to TYRB_ECOLI (397 aa), 43% identity in 397 aa overlap; Orthologue of E. coli aspC (AAT_ECOLI); Fasta hit to AAT_ECOLI (396 aa), 96% identity in 396 aa overlap; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | Succinate dehydrogenase hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). | 0.804 |
STY1000 | STY1278 | gene:17584989 | gene:17585242 | Aspartate aminotransferase; Fasta hit to TYRB_ECOLI (397 aa), 43% identity in 397 aa overlap; Orthologue of E. coli aspC (AAT_ECOLI); Fasta hit to AAT_ECOLI (396 aa), 96% identity in 396 aa overlap; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | Isocitrate dehydrogenase; Orthologue of E. coli icdA (IDH_ECOLI); Fasta hit to IDH_ECOLI (416 aa), 97% identity in 416 aa overlap. | 0.890 |
STY1000 | STY1653 | gene:17584989 | gene:17585588 | Aspartate aminotransferase; Fasta hit to TYRB_ECOLI (397 aa), 43% identity in 397 aa overlap; Orthologue of E. coli aspC (AAT_ECOLI); Fasta hit to AAT_ECOLI (396 aa), 96% identity in 396 aa overlap; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.854 |
STY1000 | STY1815 | gene:17584989 | gene:17585747 | Aspartate aminotransferase; Fasta hit to TYRB_ECOLI (397 aa), 43% identity in 397 aa overlap; Orthologue of E. coli aspC (AAT_ECOLI); Fasta hit to AAT_ECOLI (396 aa), 96% identity in 396 aa overlap; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | NADP-specific glutamate dehydrogenase; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. | 0.956 |
STY1000 | STY2561 | gene:17584989 | gene:17586460 | Aspartate aminotransferase; Fasta hit to TYRB_ECOLI (397 aa), 43% identity in 397 aa overlap; Orthologue of E. coli aspC (AAT_ECOLI); Fasta hit to AAT_ECOLI (396 aa), 96% identity in 396 aa overlap; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | Putative aminotransferase; Similar to Methylobacillus flagellatum aspartate aminotransferase aat TR:Q9RAN0 (EMBL:L78665) (429 aa) fasta scores: E(): 0, 62.1% id in 404 aa and to many putative aminotransferases; Orthologue of E. coli YFBQ_ECOLI; Fasta hit to YFBQ_ECOLI (405 aa), 97% identity in 404 aa overlap. | 0.933 |
STY1000 | STY3130 | gene:17584989 | gene:17587016 | Aspartate aminotransferase; Fasta hit to TYRB_ECOLI (397 aa), 43% identity in 397 aa overlap; Orthologue of E. coli aspC (AAT_ECOLI); Fasta hit to AAT_ECOLI (396 aa), 96% identity in 396 aa overlap; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | N-acetylglutamate synthase; Orthologue of E. coli argA (ARGA_ECOLI); Fasta hit to ARGA_ECOLI (443 aa), 94% identity in 443 aa overlap; Belongs to the acetyltransferase family. ArgA subfamily. | 0.914 |
STY1278 | STY0132 | gene:17585242 | gene:17584172 | Isocitrate dehydrogenase; Orthologue of E. coli icdA (IDH_ECOLI); Fasta hit to IDH_ECOLI (416 aa), 97% identity in 416 aa overlap. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.453 |
STY1278 | STY1000 | gene:17585242 | gene:17584989 | Isocitrate dehydrogenase; Orthologue of E. coli icdA (IDH_ECOLI); Fasta hit to IDH_ECOLI (416 aa), 97% identity in 416 aa overlap. | Aspartate aminotransferase; Fasta hit to TYRB_ECOLI (397 aa), 43% identity in 397 aa overlap; Orthologue of E. coli aspC (AAT_ECOLI); Fasta hit to AAT_ECOLI (396 aa), 96% identity in 396 aa overlap; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | 0.890 |
STY1278 | STY1653 | gene:17585242 | gene:17585588 | Isocitrate dehydrogenase; Orthologue of E. coli icdA (IDH_ECOLI); Fasta hit to IDH_ECOLI (416 aa), 97% identity in 416 aa overlap. | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.536 |
STY1278 | STY1815 | gene:17585242 | gene:17585747 | Isocitrate dehydrogenase; Orthologue of E. coli icdA (IDH_ECOLI); Fasta hit to IDH_ECOLI (416 aa), 97% identity in 416 aa overlap. | NADP-specific glutamate dehydrogenase; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. | 0.903 |
STY1278 | STY2561 | gene:17585242 | gene:17586460 | Isocitrate dehydrogenase; Orthologue of E. coli icdA (IDH_ECOLI); Fasta hit to IDH_ECOLI (416 aa), 97% identity in 416 aa overlap. | Putative aminotransferase; Similar to Methylobacillus flagellatum aspartate aminotransferase aat TR:Q9RAN0 (EMBL:L78665) (429 aa) fasta scores: E(): 0, 62.1% id in 404 aa and to many putative aminotransferases; Orthologue of E. coli YFBQ_ECOLI; Fasta hit to YFBQ_ECOLI (405 aa), 97% identity in 404 aa overlap. | 0.833 |
STY1653 | STY0776 | gene:17585588 | gene:17584782 | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Succinate dehydrogenase hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). | 0.917 |