STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY2792Extragenic suppressor protein SuhB; Fasta hit to CYSQ_ECOLI (246 aa), 31% identity in 233 aa overlap; Orthologue of E. coli suhB (SUHB_ECOLI); Fasta hit to SUHB_ECOLI (267 aa), 96% identity in 267 aa overlap; Belongs to the inositol monophosphatase superfamily. (267 aa)    
Predicted Functional Partners:
STY0457
N utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
   
 
 0.861
STY3737
Transcription antitermination protein; Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination; Bel [...]
   
 
 0.814
rpoZ
DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity).
  
   0.651
STY2287
phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase; Similar to Salmonella typhimurium histidine biosynthesis bifunctional protein HisI [includes: phosphoribosyl-AMP cyclohydrolase hisI SW:HIS2_SALTY (P10367) (203 aa) fasta scores: E(): 0, 97.5% id in 203 aa; Orthologue of E. coli hisI (HIS2_ECOLI); Fasta hit to HIS2_ECOLI (203 aa), 91% identity in 203 aa overlap; In the C-terminal section; belongs to the PRA-PH family.
  
  
 0.643
STY3468
L factor; Participates in both transcription termination and antitermination.
   
   0.635
STY2283
Imidazoleglycerol-phosphate dehydratase; Similar to Salmonella typhimurium histidine biosynthesis bifunctional protein HisB [includes: histidinol-phosphatase hisB SW:HIS7_SALTY (P10368) (354 aa) fasta scores: E(): 0, 97.5% id in 355 aa; Orthologue of E. coli hisB (HIS7_ECOLI); Fasta hit to HIS7_ECOLI (355 aa), 96% identity in 355 aa overlap; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
  
  
 0.631
STY3731
DNA-directed RNA polymerase, beta'-subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.597
STY3732
DNA-directed RNA polymerase, beta-subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.597
STY2285
Similar to Salmonella typhimurium phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase hisA SW:HIS4_SALTY (P10372) (246 aa) fasta scores: E(): 0, 96.3% id in 246 aa; Orthologue of E. coli hisA (HIS4_ECOLI); Fasta hit to HIS4_ECOLI (245 aa), 94% identity in 244 aa overlap.
 
  
 0.593
STY1981
Conserved hypothetical protein; Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.
  
  
 0.571
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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