node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
invA | invG | gene:17586913 | gene:17586915 | Possible secretory protein (associated with virulence); Involved in the invasion of the cells of the intestinal epithelium. Could be involved in the translocation of the InvE protein (By similarity); Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. | Secretory protein (associated with virulence); Highly similar to Salmonella typhimurium InvG protein precursor SW:INVG_SALTY (P35672) (562 aa) fasta scores: E(): 0, 99.1% id in 562 aa and to Shigella flexneri outer membrane protein MxiD SW:MXID_SHIFL (Q04641) (566 aa) fasta scores: E(): 0, 50.9% id in 489 aa. Contains a possible N-terminal signal sequence. | 0.995 |
invA | prgJ | gene:17586913 | gene:17586889 | Possible secretory protein (associated with virulence); Involved in the invasion of the cells of the intestinal epithelium. Could be involved in the translocation of the InvE protein (By similarity); Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. | Pathogenicity 1 island effector protein; Similar to several proteins essential for protein secretion by a type III system: Salmonella typhimurium protein PrgJ required for invasion of epithelial cells SW:PRGJ_SALTY (P41785) (101 aa) fasta scores: E(): 0, 98.0% id in 101 aa and Shigella flexneri and Shigella sonnei MxiI protein mxiI SW:MXII_SHIFL (Q06080) (97 aa) fasta scores: E(): 0.00022, 36.1% id in 97 aa. | 0.750 |
invA | prgK | gene:17586913 | gene:17586888 | Possible secretory protein (associated with virulence); Involved in the invasion of the cells of the intestinal epithelium. Could be involved in the translocation of the InvE protein (By similarity); Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. | Pathogenicity 1 island effector protein; Similar to several proteins essential for protein secretion by a type III system: Salmonella typhimurium protein precursor PrgK required for invasion of epithelial cells SW:PRGK_SALTY (P41786) (252 aa) fasta scores: E(): 0, 99.6% id in 252 aa and Shigella flexneri lipoprotein MxiJ secretion protein SW:MXIJ_SHIFL (Q06081) (241 aa) fasta scores: E(): 0, 46.1% id in 243 aa. Contains a possible N-terminal signal sequence. | 0.943 |
invA | spaI | gene:17586913 | gene:17586911 | Possible secretory protein (associated with virulence); Involved in the invasion of the cells of the intestinal epithelium. Could be involved in the translocation of the InvE protein (By similarity); Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. | Secretory apparatus ATP synthase (associated with virulence); Necessary for efficient entry of S.typhimurium into cultured epithelial cells. Probable catalytic subunit of a protein translocase. May energize the protein export apparatus encoded in the inv locus which is required for the surface presentation of determinants needed for the entry of salmonella species into mammalian cells (By similarity). | 0.999 |
invA | spaM | gene:17586913 | gene:17586910 | Possible secretory protein (associated with virulence); Involved in the invasion of the cells of the intestinal epithelium. Could be involved in the translocation of the InvE protein (By similarity); Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. | Secretory protein (associated with virulence); Similar to Salmonella typhimurium surface presentation of antigens protein spaM SW:SPAM_SALTY (P40612) (147 aa) fasta scores: E(): 0, 99.3% id in 147 aa. Contains possible coiled-coils between residues 75..110. | 0.967 |
invA | spaN | gene:17586913 | gene:17586909 | Possible secretory protein (associated with virulence); Involved in the invasion of the cells of the intestinal epithelium. Could be involved in the translocation of the InvE protein (By similarity); Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. | Surface presentation of antigens protein (associated with type III secretion and virulence); Highly similar to Salmonella typhimurium surface presentation of antigens protein SpaN SW:SPAN_SALTY (P40613) (336 aa) fasta scores: E(): 0, 98.2% id in 336 aa. | 0.993 |
invA | spaP | gene:17586913 | gene:17586907 | Possible secretory protein (associated with virulence); Involved in the invasion of the cells of the intestinal epithelium. Could be involved in the translocation of the InvE protein (By similarity); Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. | Secretory protein (associated with virulence); Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells; Belongs to the FliP/MopC/SpaP family. | 0.999 |
invA | spaQ | gene:17586913 | gene:17586906 | Possible secretory protein (associated with virulence); Involved in the invasion of the cells of the intestinal epithelium. Could be involved in the translocation of the InvE protein (By similarity); Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. | Secretory protein (associated with virulence); Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells; Belongs to the FliQ/MopD/SpaQ family. | 0.998 |
invA | spaR | gene:17586913 | gene:17586905 | Possible secretory protein (associated with virulence); Involved in the invasion of the cells of the intestinal epithelium. Could be involved in the translocation of the InvE protein (By similarity); Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. | Secretory protein (associated with virulence); Highly similar to Salmonella typhimurium surface presentation of antigens protein SpaR SW:SPAR_SALTY (P40701) (263 aa) fasta scores: E(): 0, 99.2% id in 263 aa and to Shigella flexneri SpaR SW:SPAR_SHIFL (P40706) (256 aa) fasta scores: E(): 0, 49.4% id in 235 aa. Contains possible membrane spanning hydrophobic domains. | 0.984 |
invA | spaS | gene:17586913 | gene:17586904 | Possible secretory protein (associated with virulence); Involved in the invasion of the cells of the intestinal epithelium. Could be involved in the translocation of the InvE protein (By similarity); Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. | Secretory protein (associated with virulence); Similar to Salmonella typhimurium surface presentation of antigens protein SpaS SW:SPAS_SALTY (P40702) (356 aa) fasta scores: E(): 0, 99.4% id in 356 aa. Contains possible membrane spanning hydrophobic domains. | 0.999 |
invG | invA | gene:17586915 | gene:17586913 | Secretory protein (associated with virulence); Highly similar to Salmonella typhimurium InvG protein precursor SW:INVG_SALTY (P35672) (562 aa) fasta scores: E(): 0, 99.1% id in 562 aa and to Shigella flexneri outer membrane protein MxiD SW:MXID_SHIFL (Q04641) (566 aa) fasta scores: E(): 0, 50.9% id in 489 aa. Contains a possible N-terminal signal sequence. | Possible secretory protein (associated with virulence); Involved in the invasion of the cells of the intestinal epithelium. Could be involved in the translocation of the InvE protein (By similarity); Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. | 0.995 |
invG | prgJ | gene:17586915 | gene:17586889 | Secretory protein (associated with virulence); Highly similar to Salmonella typhimurium InvG protein precursor SW:INVG_SALTY (P35672) (562 aa) fasta scores: E(): 0, 99.1% id in 562 aa and to Shigella flexneri outer membrane protein MxiD SW:MXID_SHIFL (Q04641) (566 aa) fasta scores: E(): 0, 50.9% id in 489 aa. Contains a possible N-terminal signal sequence. | Pathogenicity 1 island effector protein; Similar to several proteins essential for protein secretion by a type III system: Salmonella typhimurium protein PrgJ required for invasion of epithelial cells SW:PRGJ_SALTY (P41785) (101 aa) fasta scores: E(): 0, 98.0% id in 101 aa and Shigella flexneri and Shigella sonnei MxiI protein mxiI SW:MXII_SHIFL (Q06080) (97 aa) fasta scores: E(): 0.00022, 36.1% id in 97 aa. | 0.995 |
invG | prgK | gene:17586915 | gene:17586888 | Secretory protein (associated with virulence); Highly similar to Salmonella typhimurium InvG protein precursor SW:INVG_SALTY (P35672) (562 aa) fasta scores: E(): 0, 99.1% id in 562 aa and to Shigella flexneri outer membrane protein MxiD SW:MXID_SHIFL (Q04641) (566 aa) fasta scores: E(): 0, 50.9% id in 489 aa. Contains a possible N-terminal signal sequence. | Pathogenicity 1 island effector protein; Similar to several proteins essential for protein secretion by a type III system: Salmonella typhimurium protein precursor PrgK required for invasion of epithelial cells SW:PRGK_SALTY (P41786) (252 aa) fasta scores: E(): 0, 99.6% id in 252 aa and Shigella flexneri lipoprotein MxiJ secretion protein SW:MXIJ_SHIFL (Q06081) (241 aa) fasta scores: E(): 0, 46.1% id in 243 aa. Contains a possible N-terminal signal sequence. | 0.999 |
invG | spaI | gene:17586915 | gene:17586911 | Secretory protein (associated with virulence); Highly similar to Salmonella typhimurium InvG protein precursor SW:INVG_SALTY (P35672) (562 aa) fasta scores: E(): 0, 99.1% id in 562 aa and to Shigella flexneri outer membrane protein MxiD SW:MXID_SHIFL (Q04641) (566 aa) fasta scores: E(): 0, 50.9% id in 489 aa. Contains a possible N-terminal signal sequence. | Secretory apparatus ATP synthase (associated with virulence); Necessary for efficient entry of S.typhimurium into cultured epithelial cells. Probable catalytic subunit of a protein translocase. May energize the protein export apparatus encoded in the inv locus which is required for the surface presentation of determinants needed for the entry of salmonella species into mammalian cells (By similarity). | 0.999 |
invG | spaM | gene:17586915 | gene:17586910 | Secretory protein (associated with virulence); Highly similar to Salmonella typhimurium InvG protein precursor SW:INVG_SALTY (P35672) (562 aa) fasta scores: E(): 0, 99.1% id in 562 aa and to Shigella flexneri outer membrane protein MxiD SW:MXID_SHIFL (Q04641) (566 aa) fasta scores: E(): 0, 50.9% id in 489 aa. Contains a possible N-terminal signal sequence. | Secretory protein (associated with virulence); Similar to Salmonella typhimurium surface presentation of antigens protein spaM SW:SPAM_SALTY (P40612) (147 aa) fasta scores: E(): 0, 99.3% id in 147 aa. Contains possible coiled-coils between residues 75..110. | 0.989 |
invG | spaN | gene:17586915 | gene:17586909 | Secretory protein (associated with virulence); Highly similar to Salmonella typhimurium InvG protein precursor SW:INVG_SALTY (P35672) (562 aa) fasta scores: E(): 0, 99.1% id in 562 aa and to Shigella flexneri outer membrane protein MxiD SW:MXID_SHIFL (Q04641) (566 aa) fasta scores: E(): 0, 50.9% id in 489 aa. Contains a possible N-terminal signal sequence. | Surface presentation of antigens protein (associated with type III secretion and virulence); Highly similar to Salmonella typhimurium surface presentation of antigens protein SpaN SW:SPAN_SALTY (P40613) (336 aa) fasta scores: E(): 0, 98.2% id in 336 aa. | 0.998 |
invG | spaP | gene:17586915 | gene:17586907 | Secretory protein (associated with virulence); Highly similar to Salmonella typhimurium InvG protein precursor SW:INVG_SALTY (P35672) (562 aa) fasta scores: E(): 0, 99.1% id in 562 aa and to Shigella flexneri outer membrane protein MxiD SW:MXID_SHIFL (Q04641) (566 aa) fasta scores: E(): 0, 50.9% id in 489 aa. Contains a possible N-terminal signal sequence. | Secretory protein (associated with virulence); Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells; Belongs to the FliP/MopC/SpaP family. | 0.999 |
invG | spaQ | gene:17586915 | gene:17586906 | Secretory protein (associated with virulence); Highly similar to Salmonella typhimurium InvG protein precursor SW:INVG_SALTY (P35672) (562 aa) fasta scores: E(): 0, 99.1% id in 562 aa and to Shigella flexneri outer membrane protein MxiD SW:MXID_SHIFL (Q04641) (566 aa) fasta scores: E(): 0, 50.9% id in 489 aa. Contains a possible N-terminal signal sequence. | Secretory protein (associated with virulence); Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells; Belongs to the FliQ/MopD/SpaQ family. | 0.996 |
invG | spaR | gene:17586915 | gene:17586905 | Secretory protein (associated with virulence); Highly similar to Salmonella typhimurium InvG protein precursor SW:INVG_SALTY (P35672) (562 aa) fasta scores: E(): 0, 99.1% id in 562 aa and to Shigella flexneri outer membrane protein MxiD SW:MXID_SHIFL (Q04641) (566 aa) fasta scores: E(): 0, 50.9% id in 489 aa. Contains a possible N-terminal signal sequence. | Secretory protein (associated with virulence); Highly similar to Salmonella typhimurium surface presentation of antigens protein SpaR SW:SPAR_SALTY (P40701) (263 aa) fasta scores: E(): 0, 99.2% id in 263 aa and to Shigella flexneri SpaR SW:SPAR_SHIFL (P40706) (256 aa) fasta scores: E(): 0, 49.4% id in 235 aa. Contains possible membrane spanning hydrophobic domains. | 0.997 |
invG | spaS | gene:17586915 | gene:17586904 | Secretory protein (associated with virulence); Highly similar to Salmonella typhimurium InvG protein precursor SW:INVG_SALTY (P35672) (562 aa) fasta scores: E(): 0, 99.1% id in 562 aa and to Shigella flexneri outer membrane protein MxiD SW:MXID_SHIFL (Q04641) (566 aa) fasta scores: E(): 0, 50.9% id in 489 aa. Contains a possible N-terminal signal sequence. | Secretory protein (associated with virulence); Similar to Salmonella typhimurium surface presentation of antigens protein SpaS SW:SPAS_SALTY (P40702) (356 aa) fasta scores: E(): 0, 99.4% id in 356 aa. Contains possible membrane spanning hydrophobic domains. | 0.994 |