STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
speABiosynthetic arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. (658 aa)    
Predicted Functional Partners:
STY3238
Agmatine ureohydrolase; Catalyzes the formation of putrescine from agmatine. Belongs to the arginase family. Agmatinase subfamily.
  
 
 0.957
astA
Arginine N-succinyltransferase; Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine.
  
  
  0.912
adi
Arginine decarboxylase; Similar to Escherichia coli biodegradative arginine decarboxylase SW:ADI_ECOLI (P28629) (755 aa) fasta scores: E(): 0, 93.1% id in 755 aa, and to Escherichia coli lysine decarboxylase, constitutive SW:DCLZ_ECOLI (P52095) (713 aa) fasta scores: E(): 0, 36.2% id in 737 aa.
     
 0.909
STY3750
Argininosuccinate lyase; Orthologue of E. coli argH (ARLY_ECOLI); Fasta hit to ARLY_ECOLI (457 aa), 95% identity in 456 aa overlap.
     
 0.829
STY4805
Arginine deiminase; Similar to Pseudomonas aeruginosa arginine deiminase SW:ARCA_PSEAE (P13981) (417 aa) fasta scores: E(): 0, 46.8% id in 408 aa, and to Rhizobium etli arginine deiminase TR:O31017 (EMBL:AF025543) (409 aa) fasta scores: E(): 0, 47.3% id in 402 aa.
    
  0.815
STY3241
Similar to Escherichia coli hypothetical protein YqgB SW:YQGB_ECOLI (P46877) (48 aa) fasta scores: E(): 4.6e-10, 73.8% id in 42 aa.
       0.783
STY2986a
Hypothetical protein; Previously sequenced as Salmonella typhi hypothetical protein TR:O30622 (EMBL:AF013574) (69 aa) fasta scores: E(): 4.4e-30, 100.0% id in 69 aa.
      
 0.512
sitD
Iron transport protein, inner membrane component; Similar to Salmonella typhimurium SitD an iron transport protein located on centisome 63 pathogenicity island TR:Q9XCR9 (EMBL:AF128999) (282 aa) fasta scores: E(): 0, 99.3% id in 282 aa, and to Yersinia pestis chelated iron transport system membrane protein YfeD SW:YFED_YERPE (Q56955) (297 aa) fasta scores: E(): 0, 52.6% id in 266 aa. Contains multiple possible membrane spanning hydrophobic domains.
      
 0.502
STY1388
Putative oxidoreductase; Similar to Corynebacterium SP 2,5-diketo-D-gluconic acid reductase TR:P06632 (EMBL:M12799) (278 aa) fasta scores: E(): 0, 42.4% id in 264 aa; Fasta hit to YAFB_ECOLI (267 aa), 32% identity in 259 aa overlap; Fasta hit to P76234 (284 aa), 30% identity in 276 aa overlap; Paralogue of E. coli YQHE_ECOLI; Fasta hit to YQHE_ECOLI (275 aa), 40% identity in 257 aa overlap.
      
 0.473
STY3243
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
  
 0.426
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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