STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY3248Glutathione synthetase; Orthologue of E. coli gshB (GSHB_ECOLI); Fasta hit to GSHB_ECOLI (316 aa), 90% identity in 315 aa overlap. (315 aa)    
Predicted Functional Partners:
STY2944
Gamma-glutamylcysteine synthetase; Similar to Salmonella typhimurium LT2 glutamate--cysteine ligase SW:GSH1_SALTY (O68838) (518 aa) fasta scores: E(): 0, 98.6% id in 518 aa; Orthologue of E. coli gshA (GSH1_ECOLI); Fasta hit to GSH1_ECOLI (518 aa), 93% identity in 518 aa overlap; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
 
 
 0.984
STY4816
Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
   
 
 0.984
ggt
Similar to Escherichia coli gamma-glutamyltranspeptidase precursor ggt SW:GGT_ECOLI (P18956) (580 aa) fasta scores: E(): 0, 91.4% id in 580 aa, and to Helicobacter pylori J99 gamma-glutamyltranspeptidase ggt TR:Q9ZK95 (EMBL:AE001532) (567 aa) fasta scores: E(): 0, 52.7% id in 537 aa. Contains N-terminal signal sequence, probable secreted protein.
    
 0.977
STY0361
Aminoacyl-histidine dipeptidase precursor; Orthologue of E. coli pepD (PEPD_ECOLI); Fasta hit to PEPD_ECOLI (484 aa), 92% identity in 484 aa overlap.
     
 0.974
STY4205
Similar to Escherichia coli glutathione reductase gor SW:GSHR_ECOLI (P06715) (450 aa) fasta scores: E(): 0, 94.7% id in 450 aa, and to Haemophilus influenzae glutathione reductase HI0161 SW:GSHR_HAEIN (P43783) (456 aa) fasta scores: E(): 0, 74.8% id in 457 aa.
     
 0.928
btuE
Putative glutathione peroxidase/vitamin B12 transport periplasmic protein BtuE; Non-specific peroxidase that can use thioredoxin or glutathione as a reducing agent.
    
 0.926
STY1671
Glutathione S-transferase; Orthologue of E. coli gst (GT_ECOLI); Fasta hit to GT_ECOLI (201 aa), 83% identity in 200 aa overlap; Belongs to the GST superfamily.
  
  
 0.923
yliJ
Glutathione s-transferase family protein; Similar to Escherichia coli hypothetical 23.9 kDa protein in moea-dacc intergenic region yliJ SW:YLIJ_ECOLI (P75805) (210 aa) fasta scores: E(): 0, 83.2% id in 208 aa, and to Hyoscyamus muticus glutathione s-transferase SW:GTH_HYOMU (P46423) (212 aa) fasta scores: E(): 7.5e-13, 27.4% id in 208 aa; Orthologue of E. coli YLIJ_ECOLI; Fasta hit to YLIJ_ECOLI (210 aa), 83% identity in 208 aa overlap.
  
  
 0.919
STY2782
Peptidase B (leucyl aminopeptidase); Probably plays an important role in intracellular peptide degradation.
   
 
 0.919
STY2578
Similar to glutathione-S transferase-family proteins e.g. Dianthus caryophyllus glutathione S-transferase 1 gst1 or carsr8 SW:GTT1_DIACA (P28342) (221 aa) fasta scores: E(): 4e-07, 34.7% id in 196 aa; Orthologue of E. coli YFCF_ECOLI; Fasta hit to YFCF_ECOLI (214 aa), 81% identity in 214 aa overlap.
  
  
 0.916
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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