STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY3546aSimilar to Escherichia coli hypothetical protein YhcR SW:YHCR_ECOLI (P46478) (90 aa) fasta scores: E(): 5.6e-29, 98.5% id in 67 aa. (67 aa)    
Predicted Functional Partners:
STY3545
Putative membrane protein; Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell; Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.
 
    0.968
STY3546
Possible exported protein; Forms an efflux pump with AaeB; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
    0.941
ompX
Similar to Escherichia coli outer membrane protein x precursor ompX SW:OMPX_ECOLI (P36546) (171 aa) fasta scores: E(): 0, 91.2% id in 171 aa, and to Yersinia enterocolitica attachment invasion locus protein precursor aiL SW:AIL_YEREN (P16454) (178 aa) fasta scores: E(): 6.1e-22, 43.3% id in 180 aa; Orthologue of E. coli ompX (OMPX_ECOLI); Fasta hit to OMPX_ECOLI (171 aa), 91% identity in 171 aa overlap.
  
     0.773
STY2781
SseB protein; Orthologue of E. coli sseB (SSEB_ECOLI); Fasta hit to SSEB_ECOLI (261 aa), 89% identity in 261 aa overlap.
  
     0.770
STY3407
Putative exported protein; Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR.
  
     0.770
STY1317
Putative membrane protein; Similar to Escherichia coli YciC protein TR:BAA14787 (EMBL:D90763) (247 aa) fasta scores: E(): 0, 86.6% id in 247 aa, and to Buchnera aphidicola hypothetical protein BU276 homolog SW:Y276_BUCAP (P42396) (247 aa) fasta scores: E(): 7.5e-21, 29.5% id in 244 aa.
  
     0.769
STY1652
DNA replication terminus site-binding protein; Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence; Belongs to the Tus family.
  
     0.768
STY0517
Conserved hypothetical protein; Orthologue of E. coli ybaJ (YBAJ_ECOLI); Fasta hit to YBAJ_ECOLI (124 aa), 95% identity in 124 aa overlap.
  
     0.766
STY2722
Putative membrane protein; Similar to Escherichia coli similar to TR:P77259 (EMBL:D90875) (66 aa) fasta scores: E(): 1e-27, 95.5% id in 66 aa. Contains hydrophobic, possible membrane-spanning region.
  
     0.760
STY2924
Conserved hypothetical protein; Orthologue of E. coli ygaC (YGAC_ECOLI); Fasta hit to YGAC_ECOLI (114 aa), 88% identity in 112 aa overlap.
  
     0.759
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.