STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
STY3824L-rhamnose operon transcriptional activator; Activates expression of the rhaSR operon in response to L- rhamnose. (282 aa)    
Predicted Functional Partners:
STY3826
Rhamnulokinase; Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1- hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate. Belongs to the rhamnulokinase family.
 
  
 0.939
STY3823
L rhamnose-proton symporter; Uptake of L-rhamnose across the boundary membrane with the concomitant transport of protons into the cell (symport system). Belongs to the L-rhamnose transporter (TC 2.A.7.6) family.
 
  
 0.915
pocR
Similar to Salmonella typhimurium regulatory protein PocR pocR SW:POCR_SALTY (Q05587) (303 aa) fasta scores: E(): 0, 99.3% id in 304 aa.
 
 
 0.840
melR
Similar to Escherichia coli melibiose operon regulatory protein MelR SW:MELR_ECOLI (P10411) (302 aa) fasta scores: E(): 0, 88.3% id in 299 aa, and to Rhizobium loti regulatory protein TR:O68525 (EMBL:AF049242) (290 aa) fasta scores: E(): 5.3e-22, 27.2% id in 257 aa.
  
 
 0.833
ramA
Similar to Klebsiella pneumoniae transcriptional activator RamA ramA SW:RAMA_KLEPN (Q48413) (113 aa) fasta scores: E(): 0, 90.3% id in 113 aa, and to Escherichia coli regulatory protein SoxS soxS SW:SOXS_ECOLI (P22539) (106 aa) fasta scores: E(): 3e-18, 45.0% id in 100 aa; Paralogue of E. coli soxS (SOXS_ECOLI); Fasta hit to SOXS_ECOLI (106 aa), 45% identity in 100 aa overlap.
  
   0.762
STY1541
Multiple antibiotic resistance protein MarA; May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF (By similarity).
  
   0.759
STY1393
Similar to Escherichia coli hypothetical transcriptional regulator in eaeh-beta intergenic region ykgA SW:YKGA_ECOLI (P77601) (239 aa) fasta scores: E(): 5.5e-23, 32.7% id in 226 aa, and to Yersinia pestis putative f1 operon positive regulatory protein ypmt1.81c or caf1R TR:Q9R376 (EMBL:AL117211) (307 aa) fasta scores: E(): 2.7e-22, 32.8% id in 287 aa.
  
   0.752
STY4933
Similar to Escherichia coli right origin-binding protein roB SW:ROB_ECOLI (P27292) (289 aa) fasta scores: E(): 0, 93.1% id in 289 aa.
 
 
 0.745
STY4103
Putative L-lactate dehydrogenase operon regulator; Fasta hit to PDHR_ECOLI (254 aa), 39% identity in 254 aa overlap; Fasta hit to UXUR_ECOLI (257 aa), 32% identity in 235 aa overlap; Orthologue of E. coli lctR (LLDR_ECOLI); Fasta hit to LLDR_ECOLI (258 aa), 86% identity in 258 aa overlap.
  
  
 0.738
STY3825
L-rhamnose operon regulatory protein; Activates expression of the rhaBAD and rhaT operons.
 
 
0.736
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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