STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STY3874Glutamine synthetase; Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family. (469 aa)    
Predicted Functional Partners:
STY3510
Similar to Escherichia coli glutamate synthase [NADPH] large chain precursor GltB SW:GLTB_ECOLI (P09831) (1517 aa) fasta scores: E(): 0, 95.4% id in 1486 aa and to Pseudomonas aeruginosa glutamate synthase large subunit GltB TR:P95456 (EMBL:U81261) (1482 aa) fasta scores: E(): 0, 60.9% id in 1476 aa.
  
 
 0.995
STY1159
Proline dehydrogenase (proline oxidase); Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family.
   
 
 0.969
STY1815
NADP-specific glutamate dehydrogenase; Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.
  
 
 0.966
STY0076
Carbamoyl-phosphate synthase small chain; Orthologue of E. coli carA (CARA_ECOLI); Fasta hit to CARA_ECOLI (382 aa), 93% identity in 382 aa overlap; Belongs to the CarA family.
 
 
 0.947
STY0077
Carbamoyl-phosphate synthase large chain; Orthologue of E. coli carB (CARB_ECOLI); Fasta hit to CARB_ECOLI (1072 aa), 98% identity in 1072 aa overlap.
 
 
 0.942
STY3917
Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 
 0.940
STY3511
Glutamate synthase (NADPH) small chain; Fasta hit to P76440 (412 aa), 33% identity in 443 aa overlap; Orthologue of E. coli gltD (GLTD_ECOLI); Fasta hit to GLTD_ECOLI (471 aa), 95% identity in 471 aa overlap.
  
 
 0.939
nirB
Similar to Escherichia coli nitrite reductase [NAD nirB SW:NIRB_ECOLI (P08201) (847 aa) fasta scores: E(): 0, 95.0% id in 847 aa; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
    
 0.934
nirD
Nitrite reductase (NAD(P)H) small subunit; Required for activity of the reductase.
     
 0.927
STY2592
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
    
 0.920
Your Current Organism:
Salmonella enterica Typhi
NCBI taxonomy Id: 220341
Other names: S. enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi CT18, Salmonella enterica subsp. enterica serovar Typhi str. CT18, Salmonella enterica subsp. enterica serovar Typhi strain CT18, Salmonella typhi CT18
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